4,4'-Difluorobenzophenone - CAS 345-92-6
Catalog: |
BB022191 |
Product Name: |
4,4'-Difluorobenzophenone |
CAS: |
345-92-6 |
Synonyms: |
bis(4-fluorophenyl)methanone |
IUPAC Name: | bis(4-fluorophenyl)methanone |
Description: | 4,4'-Difluorobenzophenone (CAS# 345-92-6) is used as a reagent in the synthesis of diphenylmethoxypiperidine-derived dopamine uptake inhibitors. Also used as a reagent in the synthesis of 1-benzhydryl piperazine derivatives which display ACE inhibitor and antimicrobial activity. |
Molecular Weight: | 218.20 |
Molecular Formula: | C13H8F2O |
Canonical SMILES: | C1=CC(=CC=C1C(=O)C2=CC=C(C=C2)F)F |
InChI: | InChI=1S/C13H8F2O/c14-11-5-1-9(2-6-11)13(16)10-3-7-12(15)8-4-10/h1-8H |
InChI Key: | LSQARZALBDFYQZ-UHFFFAOYSA-N |
Boiling Point: | 137 °C (3 torr) |
Melting Point: | 106-109 °C |
Purity: | 95 % |
Density: | 1.239 g/cm3 |
Appearance: | White to off-white solid. |
Storage: | Store in a cool, dry place. Keep container closed when not in use. |
MDL: | MFCD00000353 |
LogP: | 3.19580 |
GHS Hazard Statement: | H302 (73.33%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P391, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-113429564-A | Modified polyether-ether-ketone resin capable of being rapidly photocrosslinked, and preparation method and application thereof | 20210803 |
CN-113461932-A | Preparation method of polyaryletherketone | 20210729 |
CN-113480497-A | Synthesis method of empagliflozin key intermediate | 20210727 |
CN-113480752-A | Polyether-ether-ketone reinforced master batch and preparation method thereof, and polyether-ether-ketone composite material and preparation method thereof | 20210726 |
CN-113416127-A | Cross-linkable semi-crystalline polyether-ether-ketone, preparation method and application thereof, polyether-ether-ketone polymer alloy material and preparation method thereof | 20210621 |
PMID | Publication Date | Title | Journal |
23061717 | 20121025 | Influence of chemical structure on hydration and gas transport mechanisms of sulfonated poly(aryl ether ketone) membranes | The journal of physical chemistry. B |
20491452 | 20100601 | Poly(arylene ether)s containing superacid groups as proton exchange membranes | ACS applied materials & interfaces |
21580574 | 20100303 | N-[Bis(4-fluoro-phen-yl)methyl-ene]aniline | Acta crystallographica. Section E, Structure reports online |
21583116 | 20090514 | Bis[4-(4-amino-phenyl-sulfanyl)phenyl] ketone | Acta crystallographica. Section E, Structure reports online |
18384028 | 20080101 | Role of the NH2 functionality and solvent in terdentate CNN alkoxide ruthenium complexes for the fast transfer hydrogenation of ketones in 2-propanol | Chemistry (Weinheim an der Bergstrasse, Germany) |
Complexity: | 214 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 218.05432120 |
Formal Charge: | 0 |
Heavy Atom Count: | 16 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 218.05432120 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 17.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.8 |
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