Coumarin, also known as bisfuran cyclooxaphthalone, is a lactone compound widely found in Rutaceae and Umbelliferae. Coumarin is a general term for a class of natural products with a benzo-αpyrone structure, which is widely used in medicine, fragrance, dyes, instrument analysis, agriculture and other fields.
Read MoreIndole exists in many natural products such as indole alkaloids, fungal metabolites and marine natural products. Indole derivatives have been found to contain a variety of biological activities, including antibacterial, antibiotic, anti-inflammatory, analgesic, anticonvulsant, antimalarial, anticancer, antiulcer, antileishmaniasis, contraceptive, antioxidant, etc.
Read MoreBenzimidazole is an electron-rich aromatic heterocyclic compound containing two N atoms that can form complexes with metal ions containing empty orbitals. As an important targeting pharmacophore, the high therapeutic potential of benzimidazole drugs has inspired medicinal chemists to explore the synthesis of novel chemotherapeutic agents containing benzimidazole moieties.
Read MorePyridine is a unique nitrogen-containing aromatic ring compound. Besides being widely used in industry, pyridine is also present in many natural products such as vitamins, coenzymes and alkaloids. Pyridine compounds are often used in medicine due to their basicity, water solubility, stability, hydrogen bond formation ability and small molecular size. In addition, the substitution of pyridine rings plays an important role in drug discovery.
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