Di-tert-butyl N,N-diethylphosphoramidite - CAS 117924-33-1
Catalog: |
BB004027 |
Product Name: |
Di-tert-butyl N,N-diethylphosphoramidite |
CAS: |
117924-33-1 |
Synonyms: |
N-[bis[(2-methylpropan-2-yl)oxy]phosphanyl]-N-ethylethanamine |
IUPAC Name: | N-[bis[(2-methylpropan-2-yl)oxy]phosphanyl]-N-ethylethanamine |
Description: | A useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters. |
Molecular Weight: | 249.33 |
Molecular Formula: | C12H28NO2P |
Canonical SMILES: | CCN(CC)P(OC(C)(C)C)OC(C)(C)C |
InChI: | InChI=1S/C12H28NO2P/c1-9-13(10-2)16(14-11(3,4)5)15-12(6,7)8/h9-10H2,1-8H3 |
InChI Key: | KUKSUQKELVOKBH-UHFFFAOYSA-N |
Boiling Point: | 39-41 °C (0.3 mmHg) |
Density: | 0.896 g/cm3 |
Solubility: | Hydrolyzes in water. Soluble in chloroform and methanol. |
Appearance: | Clear colourless liquid |
Storage: | Inert atmosphere, 2-8 °C |
MDL: | MFCD00134307 |
LogP: | 4.18530 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
EP-3882297-A1 | Process for producing polyether carbonate polyols | 20200317 |
WO-2021185710-A1 | Process for producing polyether carbonate polyols | 20200317 |
EP-3878885-A1 | Process for producing polyether carbonate polyols | 20200310 |
WO-2021180567-A1 | Process for preparing polyether carbonate polyols | 20200310 |
EP-3831867-A1 | Process for producing polyether carbonate polyols | 20191204 |
PMID | Publication Date | Title | Journal |
11434371 | 20010518 | Di-tert-butyl diethylphosphoramidite as the phosphitylating reagent in the preparation of 3-deoxy-3-C-methylene-D-ribo-hexose-6-phosphate and 3-deoxy-3-C-methylene-D-erythro-pentose-5-phosphate | Carbohydrate research |
8814874 | 19960201 | Solid phase synthesis of pp60src-related phosphopeptides via 'global' phosphorylation and their use as substrates for enzymatic phosphorylation by casein kinase-2 | Bioorganic & medicinal chemistry |
1280250 | 19920801 | Efficient solid phase synthesis of mixed Thr(P)-, Ser(P)- and Tyr(P)-containing phosphopeptides by 'global' 'phosphite-triester' phosphorylation | International journal of peptide and protein research |
1717394 | 19910601 | Fmoc/solid-phase synthesis of Tyr(P)-containing peptides through t-butyl phosphate protection | International journal of peptide and protein research |
Complexity: | 176 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 249.18576613 |
Formal Charge: | 0 |
Heavy Atom Count: | 16 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 249.18576613 |
Rotatable Bond Count: | 7 |
Topological Polar Surface Area: | 21.7 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3 |
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