MG-132 - CAS 133407-82-6

Catalog:	BB007748
Product Name:	MG-132
CAS:	133407-82-6
Synonyms:	Z-Leu-leu-leu-al

MG-132

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Catalog	Size	Price	Stock	Quantity
BB007748	100 mg	$239	In stock

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Computed Properties

IUPAC Name:	benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
Description:	MG-132 is a potent Proteasome inhibitor with potential anticancer activity. MG-132 induces MCPIP1 expression; induces C6 glioma cell apoptosis via oxidative stress; induces AIF nuclear translocation through down-regulation of ERK and Akt/mTOR pathway.
Molecular Weight:	475.62
Molecular Formula:	C26H41N3O5
Canonical SMILES:	CC(C)CC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1
InChI:	InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1
InChI Key:	TZYWCYJVHRLUCT-VABKMULXSA-N
Boiling Point:	682 ℃ at 760 mmHg
Density:	1.073 g/cm³
Solubility:	Soluble in ethanol, chloroform, methanol, water.
Appearance:	White crystalline
MDL:	MFCD00674886
LogP:	4.76090

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