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| IUPAC Name: | benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate |
| Description: | MG-132 is a potent Proteasome inhibitor with potential anticancer activity. MG-132 induces MCPIP1 expression; induces C6 glioma cell apoptosis via oxidative stress; induces AIF nuclear translocation through down-regulation of ERK and Akt/mTOR pathway. |
| Molecular Weight: | 475.62 |
| Molecular Formula: | C26H41N3O5 |
| Canonical SMILES: | CC(C)CC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1 |
| InChI: | InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1 |
| InChI Key: | TZYWCYJVHRLUCT-VABKMULXSA-N |
| Boiling Point: | 682 °C at 760 mmHg |
| Density: | 1.073 g/cm3 |
| Solubility: | Soluble in ethanol, chloroform, methanol, water. |
| Appearance: | White crystalline |
| MDL: | MFCD00674886 |
| LogP: | 4.76090 |
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