2-Aminobenzenesulfonamide - CAS 3306-62-5
Catalog: |
BB021540 |
Product Name: |
2-Aminobenzenesulfonamide |
CAS: |
3306-62-5 |
Synonyms: |
2-aminobenzenesulfonamide |
IUPAC Name: | 2-aminobenzenesulfonamide |
Description: | 2-Aminobenzenesulfonamide is a potent inhibitor of carbonic anhydrase B. |
Molecular Weight: | 172.20 |
Molecular Formula: | C6H8N2O2S |
Canonical SMILES: | C1=CC=C(C(=C1)N)S(=O)(=O)N |
InChI: | InChI=1S/C6H8N2O2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,7H2,(H2,8,9,10) |
InChI Key: | YAZSBRQTAHVVGE-UHFFFAOYSA-N |
Boiling Point: | 392.7 °C at 760 mmHg |
Purity: | 98 % |
Density: | 1.427 g/cm3 |
Appearance: | Solid powder |
MDL: | MFCD00007932 |
LogP: | 2.27850 |
GHS Hazard Statement: | H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] |
Precautionary Statement: | P264, P280, P305+P351+P338, and P337+P313 |
Signal Word: | Warning |
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PMID | Publication Date | Title | Journal |
22424239 | 20120412 | Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target | Journal of medicinal chemistry |
22285172 | 20120215 | Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana | Bioorganic & medicinal chemistry |
22033816 | 20111221 | Label-free detection of protein binding with multisine SPR microchips | Lab on a chip |
21757360 | 20110815 | Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates | Bioorganic & medicinal chemistry |
21251841 | 20110201 | A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth | Bioorganic & medicinal chemistry |
Complexity: | 219 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 172.03064868 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 172.03064868 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 94.6 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.2 |
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