Cysteamine hydrochloride - CAS 156-57-0
Catalog: |
BB011233 |
Product Name: |
Cysteamine hydrochloride |
CAS: |
156-57-0 |
Synonyms: |
2-Mercaptoethylamine Hydrochloride; 2-Aminoethanethiol hydrochloride; Bekaptan; CI-9148; β-Mercaptoethylamine |
Related CAS: | 60-23-1 (free base)
|
IUPAC Name: | 2-aminoethanethiol;hydrochloride |
Description: | It has been shown to increase intracellular glutathione levels in cystinotic cells, thus restoring the altered redox state of the cells. It is an antioxidant and inhibitor of DMBA-induced tumors. |
Molecular Weight: | 113.61 |
Molecular Formula: | C2H8ClNS |
Canonical SMILES: | C(CS)N.Cl |
InChI: | InChI=1S/C2H7NS.ClH/c3-1-2-4;/h4H,1-3H2;1H |
InChI Key: | OGMADIBCHLQMIP-UHFFFAOYSA-N |
Boiling Point: | 116.4 °C at 760 mmHg |
Melting Point: | 67-71 °C |
Purity: | 95 % |
Density: | 0.75 g/cm3 |
Solubility: | Slightly soluble in DMSO, Methanol, Water |
Appearance: | White to off-white solid |
Storage: | Store at -20 °C |
MDL: | MFCD00012904 |
LogP: | 1.37720 |
GHS Hazard Statement: | H302 (95.54%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P272, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501 |
Signal Word: | Warning |
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PMID | Publication Date | Title | Journal |
24337826 | 20140401 | Geraniol-a flavoring agent with multifunctional effects in protecting the gastric and duodenal mucosa | Naunyn-Schmiedeberg's archives of pharmacology |
23651769 | 20130901 | Copper deficiency in patients with cystinosis with cysteamine toxicity | The Journal of pediatrics |
23692848 | 20130801 | The SOD mimic MnTM-2-PyP(5+) reduces hyaluronan degradation-induced inflammation in mouse articular chondrocytes stimulated with Fe (II) plus ascorbate | The international journal of biochemistry & cell biology |
22898660 | 20130115 | Label-free impedimetric immunosensor for ultrasensitive detection of cancer marker Murine double minute 2 in brain tissue | Biosensors & bioelectronics |
23536773 | 20130101 | Molecules altering the intracellular thiol content modulate NF-kB and STAT-1/IRF-1 signalling pathways and IL-12 p40 and IL-27 p28 production in murine macrophages | PloS one |
Complexity: | 10 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 2 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 113.0065981 |
Formal Charge: | 0 |
Heavy Atom Count: | 5 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 3 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 113.0065981 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 27 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
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