5,6,7,8-Tetrahydropteridine - CAS 10593-78-9

Technical Data

IUPAC Name:	5,6,7,8-tetrahydropteridine
Description:	With stoichiometric amounts of the tetrahydropteridine, the initial rate of tyrosine formation is independent of both the sheep- liver enzyme and TPNH, a fact that makes it unlikely that either of these components is directly involved in the hydroxylation reaction.A putative cellular function of tetrahydropteridines was investigated in Dictyostelium discoideum Ax2 using a mutant disrupted in the gene encoding sepiapterin reductase.
Molecular Weight:	136.15
Molecular Formula:	C6H8N4
Canonical SMILES:	C1CNC2=NC=NC=C2N1
InChI:	InChI=1S/C6H8N4/c1-2-9-6-5(8-1)3-7-4-10-6/h3-4,8H,1-2H2,(H,7,9,10)
InChI Key:	IDAICLIJTRXNER-UHFFFAOYSA-N
Appearance:	Solid
References:	Kaufman, S. J. Biol. Chem., 234, 2677 (1959);Kim, H., et al. FEBS Lett, 581, 5430 (2007).

Complexity:	116
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	136.074896272
Formal Charge:	0
Heavy Atom Count:	10
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	136.074896272
Rotatable Bond Count:	0
Topological Polar Surface Area:	49.8Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	0.3