Description: | 4-[(4-Methylpiperazin-1-yl)methyl]benzaldehyde 2,2,2-Trifluoroacetate may be useful in the preparation of 2,4-substituted pyrimidines and substituted heteroaryl nitriles as cysteine protease inhibitors. It is a salt analog of 4-[(4-Methylpiperazin-1-yl)methyl]benzaldehyde (CAT# M678880), which can be useful in the development of inhibitors targeting mycobacterial tRNA modification, and synthesis of N-methylpiperazinyl flavones with therapeutic potential against Alzheimer's disease. |
Molecular Weight: | 218.29 + 114.02 |
Molecular Formula: | C13H18N2O·C2HF3O2 |
References: | Castro, P., et al. PCT Int. Appl., 181 pp., 2006:238229 (2006); Coteron, L., et al. PCT Int. Appl., 170pp., 2007:259817 (2007); Thomas, S. E., et al. Nucleic Acids Res., 48, 8099 (2020); Whitehouse, A. J., et al. J. Med. Chem., 62, 7210 (2019); Matos, A. M., et al. Pure Appl. Chem., 91, 1107 (2019); Prati, F., et al. ACS Chem. Neurosci., 6, 1665 (2015). |
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