(1S,2R)-1-Amino-2-indanol - CAS 126456-43-7

Name: (1S,2R)-1-Amino-2-indanol
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB006590
Product Name:	(1S,2R)-1-Amino-2-indanol
CAS:	126456-43-7
Synonyms:	(1S,2R)-1-amino-2,3-dihydro-1H-inden-2-ol; (1S,2R)-1-amino-2,3-dihydro-1H-inden-2-ol
Application:	(1S,2R)-1-Amino-indan-2-ol is a chiral ligand for asymmetric synthesis

Technical Data

IUPAC Name:	(1S,2R)-1-amino-2,3-dihydro-1H-inden-2-ol
Description:	(1S,2R)-(-)-cis-1-Amino-2-indanol (CAS# 126456-43-7) is a chiral ligand for asymmetric synthesis.
Molecular Weight:	149.19
Molecular Formula:	C9H11NO
Canonical SMILES:	C1C(C(C2=CC=CC=C21)N)O
InChI:	InChI=1S/C9H11NO/c10-9-7-4-2-1-3-6(7)5-8(9)11/h1-4,8-9,11H,5,10H2/t8-,9+/m1/s1
InChI Key:	LOPKSXMQWBYUOI-BDAKNGLRSA-N
Boiling Point:	~290.0 °C (Predicted) / 760 mmHg
Melting Point:	118-121 °C
Purity:	≥ 99 %
Density:	~1.2 g/mL (Predicted)
Solubility:	Soluble in water (slightly), and methanol.
Appearance:	Powder or crystals
Storage:	Keep in dark place. Inert atmosphere. Room temperature.
MDL:	MFCD00216655
LogP:	1.30370
Refractive Index:	1.63

GHS Hazard Statement:	H315 (94.81%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

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PMID	Publication Date	Title	Journal
22260086	20120203	Enantioselective acylation of 1,2- and 1,3-diols catalyzed by aminophosphinite derivatives of (1S,2R)-1-amino-2-indanol	Organic letters
20617835	20100806	Asymmetric synthesis of chiral primary amines by transfer hydrogenation of N-(tert-butanesulfinyl)ketimines	The Journal of organic chemistry
16302257	20060205	Synthesis of enantiomerically pure trans-(1R,2R)- and cis-(1S,2R)-1-amino-2-indanol by lipase and omega-transaminase	Biotechnology and bioengineering
15200330	20040624	Epimerization of diastereomeric alpha-amino nitriles to single stereoisomers in the solid state	Organic letters
11738583	20020107	Potent P1' biphenylmethyl substituted aggrecanase inhibitors	Bioorganic & medicinal chemistry letters

Complexity:	149
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	2
Defined Bond Stereocenter Count:	0
Exact Mass:	149.084063974
Formal Charge:	0
Heavy Atom Count:	11
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	149.084063974
Rotatable Bond Count:	0
Topological Polar Surface Area:	46.2 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	0.2