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Application Area

  • Medicinal Chemistry

    Medicinal Chemistry

    Medicinal chemistry and drug research require diverse chemical components to meet strict requirements not only in terms of physical and chemical properties but also in terms of chemical reactivity.

  • Organic Chemistry

    Organic Chemistry

    The chemists use the 'build–couple–pair' strategy of organic synthesis, which entails preparing molecular building blocks that contain several chemical groups.

  • Material chemistry

    Material chemistry

    The chemical building block (CBB) is a molecule which can be converted to various secondary chemicals and intermediates, and, in turn, into a broad range of different downstream uses.


  • Catalog: BB044081
  • Molecular Weight: 128.17
  • Molecular Formula: C6H12N2O
  • Catalog: BB041781
  • Molecular Weight: 216.281
  • Molecular Formula: C10H20N2O3
  • Catalog: BB054411
  • Molecular Weight: 117.15
  • Molecular Formula: C5H11NO2
  • Catalog: BB042479
  • Molecular Weight: 209.71
  • Molecular Formula: C12H16ClN
  • Catalog: BB038188
  • Molecular Weight: 213.325
  • Molecular Formula: C11H23N3O
  • Catalog: BB053265
  • Molecular Weight: 239.34
  • Molecular Formula: C12H17NO2S
  • Catalog: BB032832
  • Molecular Weight: 142.202
  • Molecular Formula: C7H14N2O
  • Catalog: BB032700
  • Molecular Weight: 149.618
  • Molecular Formula: C6H12ClNO
  • Catalog: BB031315
  • Molecular Weight: 220.316
  • Molecular Formula: C13H20N2O
  • Catalog: BB042384
  • Purity: 98 %
  • Molecular Weight: 226.32
  • Molecular Formula: C12H22N2O2


Diazepan, chemical formula C16H13ClN2O, belongs to the class of benzodiazepines. As a 1,4-benzodiazepine and organochlorine compound, diazepam has effects as xenobiotics, environmental pollutants, anxiolytics, anticonvulsants and sedatives.


Mechanism of Action

Diazepan acts on the GABAA receptor complex, a receptor for gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the body (the complex contains GABA receptors, benzodiazepine receptors and a chloride channel coupled to GABA receptors), and this interaction between the drug and the receptor induces enhanced opening of the chloride channel coupled to GABA receptors, which increases the influx of chloride ions into the cell, generating hyperpolarization and inhibiting postsynaptic potentials, causing central inhibition. This increases the amount of chloride ions flowing into the cell, producing hyperpolarization and suppressing postsynaptic potentials, reducing the firing of some important neurons in the center, and causing central depression. It is a neuroleptic drug that, along with alcohol and opioids, can be used to alleviate the withdrawal response to alcohol, but long-term use can also lead to dependence.


Clinical Application of Diazepan

1) Anxiety disorders and various functional neuroses. 2) Insomnia, especially for anxiety insomnia with excellent efficacy. 3) Epilepsy, it can be used in combination with other antiepileptic drugs to treat grand mal or petit mal seizures, and should be injected intravenously when controlling persistent status epilepticus. 4) Convulsions caused by various reasons, such as eclampsia, tetanus, pediatric fever convulsions, etc. 5) Muscle spasms caused by cerebrovascular accident or spinal cord injury with central muscle tonicity or lumbar muscle strain, endoscopy, etc. 6) Others: migraine, myotonic headache, eruption, inflammation-induced reflex muscle spasm, panic disorder, alcohol withdrawal syndrome, and also for familial, geriatric and idiopathic tremor, which can be used for preanesthetic administration.

If you are interested in our azepan/diazepan products, please contact us immediately!

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