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| Description: | (Z)-Ethyl 4-(2-(tert-butoxy)-2-oxoethoxy)-2-(2-chlorobenzylidene)-3-oxobutanoate is an intermediate for the synthesis of O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine (D289480), which is the metablolite of Amlodipine (A633495), a long-acting calcium channel blocker that is commonly used as an anti-hypertensive in the treatment of cardiovascular conditions. |
| Molecular Weight: | 382.84 |
| Molecular Formula: | C19H23ClO6 |
| References: | Arrowsmith, J.E., et al. J. Med. Chem., 29, 1696 (1986), Burges, R.A., et al. J. Cardiovasc. Pharmacol., 9, 110 (1987), Haria, M., et al. Drugs, 50, 560 (1995). |
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