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| Description: | (Z)-Ethyl 3-(4-Benzylphenyl)-2-cyanobut-2-enoate is an intermediate in synthesizing Barbadin (B118250), a selective β-arrestin/β2-adaptin inhibitor. It selectively inhibits the interaction between b-arrestin and the b2-adaptin subunit of the clathrin adaptor protein AP2 without affecting the formation of receptor/b-arrestin complexes. |
| Molecular Weight: | 305.37 |
| Molecular Formula: | C20H19NO2 |
| References: | Beautrait, A., et al. Nat Commun. 8, 15054 (2017). |
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