Description: | (Z)-7-((S)-2-Azido-2-carboxyethyl)thio Cilastatin Derivative is an intermediate in the synthesis of (Z)-7-(((2R)-2-Carboxy-2-((4-oxopentan-2-yl)amino)ethyl)thio)-2-((S)-2,2-dimethylcyclopropanecarboxamido)hept-2-enoic Acid (C178930), an impurity of Cilastatin (C441100), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct. |
Molecular Weight: | 384.45 |
Molecular Formula: | C16H24N4O5S |
Solubility: | Dichloromethane |
Appearance: | Yellow syrup |
Storage: | -20°C |
References: | Finlay, K.R., et al. Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al. Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al. J. Antimicrob. Chemother., 12, 39 (1983),. |
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