(Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic Acid - CAS 75028-24-9

Name: (Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic Acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB035226
Product Name:	(Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic Acid
CAS:	75028-24-9
Synonyms:	(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-ethoxyiminoacetic acid; (2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-ethoxyiminoacetic acid

Technical Data

IUPAC Name:	(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-ethoxyiminoacetic acid
Description:	(Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic Acid (CAS# 75028-24-9) is an important intermediate for the preparation of Ceftaroline which possesses antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and P. aeruginosa.
Molecular Weight:	216.22
Molecular Formula:	C6H8N4O3S
Canonical SMILES:	CCON=C(C1=NSC(=N1)N)C(=O)O
InChI:	InChI=1S/C6H8N4O3S/c1-2-13-9-3(5(11)12)4-8-6(7)14-10-4/h2H2,1H3,(H,11,12)(H2,7,8,10)/b9-3-
InChI Key:	UFTDZEXQFNFPFR-OQFOIZHKSA-N
MDL:	MFCD14583152
LogP:	0.52670

Publication Number	Title	Priority Date
US-2019100534-A1	Cephem Compounds with Latent Reactive Groups	20171004
EP-2788361-A1	Process for preparing ceftaroline salts or hydrates thereof	20111207
US-2014350240-A1	Process for preparing ceftaroline salts or hydrates thereof	20111207
WO-2013084171-A1	Process for preparing ceftaroline salts or hydrates thereof	20111207
WO-2010123997-A1	Carbacephem beta-lactam antibiotics	20090422

Complexity:	247
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	1
Exact Mass:	216.0317113
Formal Charge:	0
Heavy Atom Count:	14
Hydrogen Bond Acceptor Count:	8
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	216.0317113
Rotatable Bond Count:	4
Topological Polar Surface Area:	139
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1.1