UA 45336 - CAS 13972-97-9
Catalog: |
BB056947 |
Product Name: |
UA 45336 |
CAS: |
13972-97-9 |
Synonyms: |
NS 45336; 1,2-Dihydro-4-hydroxy-1-oxo-3-Isoquinolinecarboxylic Acid Methyl Ester |
IUPAC Name: | methyl 4-hydroxy-1-oxo-2H-isoquinoline-3-carboxylate |
Description: | UA 45336 is a precursor to FG 2216 (F329000) which is an erythropoietic agent which is orally active prolyl-hydroxylase inhibitor which increases erythropoietin production in end-stage kidney disease. |
Molecular Weight: | 219.19 |
Molecular Formula: | C11H9NO4 |
Canonical SMILES: | COC(=O)C1=C(C2=CC=CC=C2C(=O)N1)O |
InChI: | InChI=1S/C11H9NO4/c1-16-11(15)8-9(13)6-4-2-3-5-7(6)10(14)12-8/h2-5,13H,1H3,(H,12,14) |
InChI Key: | JOURGLFWVLLAPY-UHFFFAOYSA-N |
References: | Bernhardt, W., et al. J Am Soc Nephrol, 21, 2151 (2010). |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
AU-2006243245-A1 | Heterocyclic antiviral compounds | 20050504 |
BR-PI0611388-A2 | heterocyclic antiviral compounds, their use and pharmaceutical composition | 20050504 |
CA-2607089-A1 | Heterocyclic antiviral compounds | 20050504 |
CN-101189230-A | Heterocyclic antiviral compounds | 20050504 |
EP-1879885-A1 | Heterocyclic antiviral compounds | 20050504 |
JP-2008540370-A | Heterocyclic antiviral compounds | 20050504 |
KR-20070116682-A | Heterocyclic antiviral compounds | 20050504 |
MX-2007013415-A | HETEROCICLIC ANTIVIRAL COMPOUNDS. | 20050504 |
US-2006252785-A1 | Heterocyclic antiviral compounds | 20050504 |
US-7674810-B2 | 1,1-dioxo-1H-1Î>6-benzo[d]isothiazol-3-yl)-4-hydroxy-1,5-dihydro-pyrrol-2-one inhibitors of HCV polymerase | 20050504 |
Complexity: | 361 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 219.05315777 |
Formal Charge: | 0 |
Heavy Atom Count: | 16 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 219.05315777 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 75.6Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.3 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Other Building Blocks
-
[147396-07-4]C10H9NOS
(E)-1-(Benzo[b] thiophen- 2- yl)ethanone Oxime
-
C50H68O34
Maltotetraose Tridecaacetate
-
C18H29N5O2
(3R,4R)-tert-Butyl 3-((6,7-Dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidine-1-carboxylate
-
[24177-07-9]C17H26N2O6
(2R,5S,10aS,10bS)-Octahydro-10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine-2-carboxylic Acid
-
C14H20N2O6
(2R,5S,10aS,10bS)-10b-Hydroxy-5-isopropyl-2-methyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine-2-carboxylic Acid
-
[31431-28-4]C14H12N2O3
(4-Amino-3-nitrophenyl)(4-methylphenyl)-methanone
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS