Tyramine - CAS 51-67-2

Name: Tyramine
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB027545
Product Name:	Tyramine
CAS:	51-67-2
Synonyms:	Phenol, 4-(2-aminoethyl)-; Phenol, p-(2-aminoethyl)-; 2-(4-Hydroxyphenyl)ethanamine; 2-(4-Hydroxyphenyl)ethylamine; 2-(4'-Hydroxyphenyl)ethylamine; 2-(p-Hydroxyphenyl)ethylamine; 4-Hydroxy-β-phenylethylamine; 4-Hydroxyphenethylamine; 4-Hydroxyphenylethylamine; Benzeneethanamine, 4-hydroxy-; NSC 249188; p-(2-Aminoethyl)phenol; p-Hydroxy-β-phenylethylamine; p-Hydroxyphenethylamine; p-Hydroxyphenylethylamine; p-Tyramine; p-β-Aminoethylphenol; Systogene; Tocosine; Tyramin; Tyramine; Tyrosamine; Uteramine; α-(4-Hydroxyphenyl)-β-aminoethane; β-(4-Hydroxyphenyl)ethylamine; Tylosin EP Impurity II

Technical Data

Related CAS:	60-19-5 (monohydrochloride)
IUPAC Name:	4-(2-aminoethyl)phenol
Description:	Tylosin EP Impurity II, an impurity of Tylosin, is a natural compound derived from tyrosine in cheese and other foods. It acts as a neurotransmitter via a G protein-coupled receptor named TA1.
Molecular Weight:	137.18
Molecular Formula:	C8H11NO
Canonical SMILES:	C1=CC(=CC=C1CCN)O
InChI:	InChI=1S/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2
InChI Key:	DZGWFCGJZKJUFP-UHFFFAOYSA-N
Boiling Point:	166°C
Melting Point:	164-165°C
Purity:	≥95%
Density:	1.103±0.06 g/cm3
Solubility:	Soluble in DMSO (Slightly), Methanol (Slightly)
Appearance:	Light Yellow to Dark Brown Solid
Storage:	Store at 2-8°C under inert atmosphere
MDL:	MFCD00008193
LogP:	1.59370

GHS Hazard Statement:	H315 (95.74%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
CN-113373097-A	Lactobacillus plantarum and application thereof	20210727
CN-113481112-A	Zygosaccharomyces rouxii and application thereof in reducing biogenic amine in soy sauce	20210720
CN-113501981-A	Single-component biological hydrogel and preparation method and application thereof	20210716
CN-113249268-A	Saccharopolyspora rosea for reducing biogenic amine and application thereof	20210625
CN-113249350-A	Copper-containing amine oxidase capable of degrading biogenic amine and derived from saccharopolyspora hopogonii and application of copper-containing amine oxidase	20210625

PMID	Publication Date	Title	Journal
33913699	20210517	Nonclinical Evaluation of Antibacterial Oxazolidinones Contezolid and Contezolid Acefosamil with Low Serotonergic Neurotoxicity	Chemical research in toxicology
31862286	20200301	Graphene oxide-induced neurotoxicity on neurotransmitters, AFD neurons and locomotive behavior in Caenorhabditis elegans	Neurotoxicology
31124249	20191001	Glucosylation of the phytoalexin N-feruloyl tyramine modulates the levels of pathogen-responsive metabolites in Nicotiana benthamiana	The Plant journal : for cell and molecular biology
29655911	20180501	Antinociceptive activity of Riparin II from Aniba riparia: Further elucidation of the possible mechanisms	Chemico-biological interactions
27139242	20170501	Pharmacological characterization of histamine-gated chloride channels from the housefly Musca domestica	Neurotoxicology

Complexity:	87.3
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	137.084063974
Formal Charge:	0
Heavy Atom Count:	10
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	137.084063974
Rotatable Bond Count:	2
Topological Polar Surface Area:	46.2 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1.1