trans-Cinnamic acid - CAS 140-10-3

Catalog:	BB009034
Product Name:	trans-Cinnamic acid
CAS:	140-10-3
Synonyms:	2-Propenoic acid, 3-phenyl-, (2E)-; (2E)-3-Phenyl-2-propenoic acid; 2-Propenoic acid, 3-phenyl-, (E)-; Cinnamic acid, (E)-; (2E)-2-Phenyl-2-propenoic acid; (2E)-3-Phenylprop-2-enoic acid; (2E)-Cinnamic acid; (E)-3-Phenyl-2-propenoic acid; (E)-3-Phenylacrylic acid; (2E)-3-Phenylacrylic acid; (E)-Cinnamic acid; 3-Phenyl-(E)-2-propenoic acid; NSC 44010; trans-3-Phenyl-2-propenoic acid; trans-3-Phenylacrylic acid; trans-β-Carboxystyrene
Application:	Anaesthetic, anthelmintic.

Technical Data

Related CAS:	621-82-9 (rac-isomer) 102-94-3 (Z-isomer)
IUPAC Name:	(E)-3-phenylprop-2-enoic acid
Description:	Cinnamic acid exerts anti-diabetic activity by improving glucose tolerance in vivo and stimulating insulin secretion in vitro.
Molecular Weight:	148.16
Molecular Formula:	C9H8O2
Canonical SMILES:	C1=CC=C(C=C1)C=CC(=O)O
InChI:	InChI=1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+
InChI Key:	WBYWAXJHAXSJNI-VOTSOKGWSA-N
Boiling Point:	300°C
Melting Point:	133°C
Flash Point:	189.5°C
Purity:	≥95%
Density:	1.184±0.06 g/cm3
Solubility:	Soluble in Chloroform (Slightly), Methanol (Slightly)
Appearance:	White to Off-white Solid
Storage:	Store at 2-8°C
MDL:	MFCD00004369
LogP:	1.78440
Quality Standard:	Enterprise Standard
Refractive Index:	1.555 (20°C)
Stability:	Stable under normal temperatures and pressures.

GHS Hazard Statement:	H315 (80.9%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
AU-2021105675-A4	Treatment of by-products of plant industry	20210816
CN-113461884-A	Modified phenolic resin for photoresist and preparation method thereof	20210804
CN-113424917-A	Sugui fragrant ginger meal replacement powder and preparation method thereof	20210714
CN-113376281-A	Method for simultaneously detecting 14 metabolites in lycoris plant alkaloid synthesis pathway	20210610
KR-102289125-B1	A cosmetic composition comprising Robinia pseudoacacia flower extract	20210602

PMID	Publication Date	Title	Journal
33049310	20210401	Evaluation of a multiplexed, multispecies nuclear receptor assay for chemical hazard assessment	Toxicology in vitro : an international journal published in association with BIBRA
30048736	20181201	Synthesis and antimetastatic activity evaluation of cinnamic acid derivatives containing 1,2,3-triazolic portions	Toxicology in vitro : an international journal published in association with BIBRA
30144576	20181201	Glucotoxicity results in apoptosis in H9c2 cells via alteration in redox homeostasis linked mitochondrial dynamics and polyol pathway and possible reversal with cinnamic acid	Toxicology in vitro : an international journal published in association with BIBRA
29653686	20180501	Pegvaliase for the treatment of phenylketonuria: Results of a long-term phase 3 clinical trial program (PRISM)	Molecular genetics and metabolism
29369483	20180301	Eudesmanolides and Other Constituents from the Flowers of Wedelia trilobata	Chemistry & biodiversity

Complexity:	155
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	1
Exact Mass:	148.052429494
Formal Charge:	0
Heavy Atom Count:	11
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	1
Isotope Atom Count:	0
Monoisotopic Mass:	148.052429494
Rotatable Bond Count:	2
Topological Polar Surface Area:	37.3 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	2.1