Tetraethylene glycol monotosylate - CAS 77544-60-6
Catalog: |
BB035988 |
Product Name: |
Tetraethylene glycol monotosylate |
CAS: |
77544-60-6 |
Synonyms: |
Tos-PEG4; Tos-PEG4-OH; Tetraethyleneglycol monotosylate; 2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]ethyl tosylate |
IUPAC Name: | 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate |
Description: | Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Molecular Weight: | 348.41 |
Molecular Formula: | C15H24O7S |
Canonical SMILES: | CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCO |
InChI: | InChI=1S/C15H24O7S/c1-14-2-4-15(5-3-14)23(17,18)22-13-12-21-11-10-20-9-8-19-7-6-16/h2-5,16H,6-13H2,1H3 |
InChI Key: | FGDJUEZBMFELRW-UHFFFAOYSA-N |
Flash Point: | >230 °F |
Purity: | > 98.0 % |
Solubility: | 10 mm in DMSO |
Appearance: | Colourless to light (or pale) yellow liquid |
Storage: | -20 °C |
LogP: | 1.21000 |
Publication Number | Title | Priority Date |
US-2021315896-A1 | Indazole based compounds and associated methods of use | 20200321 |
WO-2021194879-A1 | Indazole based compounds and associated methods of use | 20200321 |
CN-111233822-A | Crown ether modified ligand, four-metal Pt rectangular supramolecular complex, and preparation method and application thereof | 20200306 |
CN-111233822-B | Crown ether modified ligand, four-metal Pt rectangular supramolecular complex, and preparation method and application thereof | 20200306 |
WO-2021178339-A1 | Heterobifunctional molecules as tead inhibitors | 20200304 |
Complexity: | 372 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 348.12427427 |
Formal Charge: | 0 |
Heavy Atom Count: | 23 |
Hydrogen Bond Acceptor Count: | 7 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 348.12427427 |
Rotatable Bond Count: | 13 |
Topological Polar Surface Area: | 99.7 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.3 |
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