Tetraethylene glycol - CAS 112-60-7

Technical Data

IUPAC Name:	2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethanol
Description:	Tetraethylene glycol is a polyethylene glycol (PEG)-based PROTAC linker. Tetraethylene glycol can be used in the synthesis of a series of PROTACs.
Molecular Weight:	194.23
Molecular Formula:	C8H18O5
Canonical SMILES:	C(COCCOCCOCCO)O
InChI:	InChI=1S/C8H18O5/c9-1-3-11-5-7-13-8-6-12-4-2-10/h9-10H,1-8H2
InChI Key:	UWHCKJMYHZGTIT-UHFFFAOYSA-N
Boiling Point:	324-330°C
Melting Point:	-4.1°C
Flash Point:	360 °F
Purity:	98%
Density:	1.125
Solubility:	Miscible with water /1.0X10+6 mg/L/ at 20 °C
Appearance:	Colorless Liquid
Storage:	Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Decomposition:	When heated to decomposition it emits acrid smoke and irritating fumes
Vapor Pressure:	4.65X10-5 mm Hg at 26 °C

GHS Hazard Statement:	H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Precautionary Statement:	P264+P265, P280, P305+P351+P338, and P337+P317
Signal Word:	Warning

Complexity:	78.6
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	194.11542367
Formal Charge:	0
Heavy Atom Count:	13
Hydrogen Bond Acceptor Count:	5
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	194.11542367
Rotatable Bond Count:	10
Topological Polar Surface Area:	68.2
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	-1.6