IUPAC Name: | tert-butyl N-[(4S)-2,6-dimethyl-3-oxohept-1-en-4-yl]carbamate |
Description: | tert-Butyl ((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)carbamate is an intermediate in the synthesis of (S)-2-Amino-4-methyl-1-((S)-2-methyloxiran-2-yl)pentan-1-one Trifluoroacetate Salt which is an impurity of carfilzomib (C183460). Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. |
Molecular Weight: | 255.35 |
Molecular Formula: | C14H25NO3 |
Canonical SMILES: | CC(C)CC(C(=O)C(=C)C)NC(=O)OC(C)(C)C |
InChI: | InChI=1S/C14H25NO3/c1-9(2)8-11(12(16)10(3)4)15-13(17)18-14(5,6)7/h9,11H,3,8H2,1-2,4-7H3,(H,15,17)/t11-/m0/s1 |
InChI Key: | BRMIWZWAGRRHEN-NSHDSACASA-N |
Appearance: | Solid |
References: | Fostier, K., et al. Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al. J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al. Drugs., 72, 2023 (2012). |
Customer Support
If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?
Customer Centered
Related Functional Groups
Other Building Blocks
Customers Also Viewed
Copyright © 2024 BOC Sciences. All rights reserved.
Our Products