![tert-Butyl 3-Bromo-1-(tetrahydro-2H-pyran-4-yl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate](https://resource.bocsci.com/structure/1936429-15-0.gif)
Inquiry Basket
| IUPAC Name: | tert-butyl 3-bromo-1-(oxan-4-yl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxylate |
| Description: | tert-Butyl 3-Bromo-1-(tetrahydro-2H-pyran-4-yl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate is an intermediate in the synthesis of GNE-781 (D447825), a derivative of a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology. |
| Molecular Weight: | 386.28 |
| Molecular Formula: | C16H24BrN3O3 |
| Canonical SMILES: | CC(C)(C)OC(=O)N1CCC2=C(C1)C(=NN2C3CCOCC3)Br |
| InChI: | InChI=1S/C16H24BrN3O3/c1-16(2,3)23-15(21)19-7-4-13-12(10-19)14(17)18-20(13)11-5-8-22-9-6-11/h11H,4-10H2,1-3H3 |
| InChI Key: | KLNNZNTUBJKEBX-UHFFFAOYSA-N |
| Solubility: | Dichloromethane |
| Appearance: | Yellow Foam |
| References: | Romero, F.A.; et al. J. Med. Chem, DOI: 10.1021/acs.jmedchem.7b00796 (2017). |
![[2-(trifluoromethyl)oxan-4-yl]methanamine](https://resource.bocsci.com/structure/1865148-77-1.gif)
Catalog: BB014333
[2-(trifluoromethyl)oxan-4-yl]methanamine
Detail
Catalog: BB054808
2-(4-Aminooxan-3-yl)acetic Acid
Detail
Catalog: BB002009
Ethylenesulfate
Detail
Catalog: BB014781
1,4-Benzodioxane-6-carbonitrile
Detail
Catalog: BB016397
1-methyl-3-(1,3-thiazol-2-yl)-1H-pyrazole-5-carbaldehyde
Detail
Catalog: BB043274
Ethylferrocene
Detail
![4-chloro-6-methylimidazo[2,1-f][1,2,4]triazine](https://resource.bocsci.com/structure/2090251-00-4.gif)
Catalog: BB016398
4-chloro-6-methylimidazo[2,1-f][1,2,4]triazine
Detail
![2-amino-3-{pyrrolo[2,1-f][1,2,4]triazin-5-yl}propanenitrile](https://resource.bocsci.com/structure/2092670-62-5.gif)
Catalog: BB016437
2-amino-3-{pyrrolo[2,1-f][1,2,4]triazin-5-yl}propanenitrile
Detail
Customer Support
If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?
Customer Centered
Global Delivery
Warehouses in multiple cities to ensure fast delivery
Quality Assurance
Strict process parameter control to ensure product quality
Large Stock
> 20,000 building blocks and intermediates from stock
Process Scale-up
Process scale-up from lab to industrial scale
Flexible Batch Size
Flexible batch size for diverse industrial demandsRelated Functional Groups
Other Building Blocks
Customers Also Viewed
Copyright © 2024 BOC Sciences. All rights reserved.
Our Products
