Description: | tert-Butyl ((1r,3s,5R,7S)-3-Nitroadamantan-1-yl)carbamate is an intermediate in the synthesis of 1-Amino-3-nitroadamantane (A618130) which has potential application in co-catalyst for transition metal reactions and maybe a useful intermediate for the synthesis of Vildagliptin (V305000), an antidiabetic drug that inhibits dipeptidyl peptidase 4 (DPP-4). Vildagliptin exhibits antioxidant properties and may be an apoptotic compound against pancreatic cancer cells. |
Molecular Weight: | 296.37 |
Molecular Formula: | C15H24N2O4 |
References: | Amritha, C., et al. JCDR 9, FC14 (2015); Ahren, B., et al. J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al. Diabetes Care, 27, 2874 (2004), Barlocco, D., et al. Curr. Opin. Invest. Drugs, 5, 1094 (2004). |
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