Hydroxy-PEG6-t-butyl ester - CAS 361189-64-2
Catalog: |
BB022866 |
Product Name: |
Hydroxy-PEG6-t-butyl ester |
CAS: |
361189-64-2 |
Synonyms: |
HO-PEG6-CH2CH2COOtBu; Hydroxy-PEG6-(CH2)2-Boc; OH-PEG6-TBA; OH-PEG6-CH2CH2COOtBu; HO-PEG6-t-butyl ester; tert-butyl 1-hydroxy-3,6,9,12,15,18-hexaoxahenicosan-21-oate; 2-Methyl-2-propanyl 1-hydroxy-3,6,9,12,15,18-hexaoxahenicosan-21-oate; 3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-hydroxy-, 1,1-dimethylethyl ester |
Related CAS: | 1186025-29-5 (polymer) 892154-71-1 (polymer)
|
IUPAC Name: | tert-butyl 3-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
Description: | Hydroxy-PEG6-t-butyl ester is a PEG linker containing a hydroxyl group and a t-butyl ester. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl-protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media. |
Molecular Weight: | 410.50 |
Molecular Formula: | C19H38O9 |
Canonical SMILES: | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCO |
InChI: | InChI=1S/C19H38O9/c1-19(2,3)28-18(21)4-6-22-8-10-24-12-14-26-16-17-27-15-13-25-11-9-23-7-5-20/h20H,4-17H2,1-3H3 |
InChI Key: | VGGDPFAYSOSIOK-UHFFFAOYSA-N |
Boiling Point: | 481.8±40.0 °C at 760 mmHg |
Purity: | ≥95% |
Density: | 1.076±0.06 g/cm3 (Predicted) |
Appearance: | Pale Yellow or Colorless Oily Liquid |
Storage: | Store at 2-8°C |
LogP: | 0.81010 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021195295-A1 | Bifunctional molecules and methods of using thereof | 20200324 |
US-2018161446-A1 | Antibody drug conjugate, intermediate, preparation method, pharmaceutical composition and uses thereof | 20150609 |
EP-2917195-A1 | Spliceostatin analogs | 20121105 |
EP-2917195-B9 | Spliceostatin analogs | 20121105 |
US-2014134193-A1 | Spliceostatin analogs and methods for their preparation | 20121105 |
Complexity: | 345 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 410.25158279 |
Formal Charge: | 0 |
Heavy Atom Count: | 28 |
Hydrogen Bond Acceptor Count: | 9 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 410.25158279 |
Rotatable Bond Count: | 22 |
Topological Polar Surface Area: | 102 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.5 |
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