Tafenoquine-d3 Succinate

Catalog: BB076690
Product Name: Tafenoquine-d3 Succinate
Synonyms: N4-[2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]-8-quinolinyl]-1,4-pentanediamine-d3;Tafenoquine-d3; WR 238605-d3
Tafenoquine-d3 Succinate
IUPAC Name:butanedioic acid4-N-[6-methoxy-4-methyl-2-(trideuteriomethoxy)-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine
Description:Tafenoquine-d3 Succinate is the labelled analog of Tatenoquine (T004760), a new 8-aminoquinoline with an improved therapeutic index and safety profile as compared to primaquine (P733500).Tafenoquine has the potential to become a widely used drug in the prevention and treatment of malaria infection and could replace some currently used drugs as resistant strains of Plasmodium species increase.
Molecular Weight:584.6
Molecular Formula:C28H31D3F3N3O7
Canonical SMILES:CC1=CC(=NC2=C1C(=C(C=C2NC(C)CCCN)OC)OC3=CC=CC(=C3)C(F)(F)F)OC.C(CC(=O)O)C(=O)O
InChI:InChI=1S/C24H28F3N3O3.C4H6O4/c1-14-11-20(32-4)30-22-18(29-15(2)7-6-10-28)13-19(31-3)23(21(14)22)33-17-9-5-8-16(12-17)24(25,26)275-3(6)1-2-4(7)8/h5,8-9,11-13,15,29H,6-7,10,28H2,1-4H31-2H2,(H,5,6)(H,7,8)/i4D3
InChI Key:CQBKFGJRAOXYIP-NXIGQQGZSA-N
References:McIntyre, J. A., et al. Drugs. Future., 28, 859 (2003); LaMontagne, M.P., et al. J. Medn. Chem., 32, 1728 (1989).

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