t-Boc-N-amido-PEG6-alcohol - CAS 331242-61-6
Catalog: |
BB021565 |
Product Name: |
t-Boc-N-amido-PEG6-alcohol |
CAS: |
331242-61-6 |
Synonyms: |
NHBoc-PEG6-OH; N-Boc-PEG6-alcohol; N-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamic acid tert-butyl ester; 17-(Boc-amino)-3,6,9,12,15-pentaoxa-1-heptadecanol; Boc-NH-PEG6-OH; tert-Butyl (17-hydroxy-3,6,9,12,15-pentaoxaheptadecyl)carbamate; 2-Methyl-2-propanyl (17-hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl)carbamate; Carbamic acid, N-(17-hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl)-, 1,1-dimethylethyl ester |
Related CAS: | 159156-95-3 (polymer)
|
IUPAC Name: | tert-butyl N-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate |
Description: | N-Boc-PEG6-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Molecular Weight: | 381.46 |
Molecular Formula: | C17H35NO8 |
Canonical SMILES: | CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCO |
InChI: | InChI=1S/C17H35NO8/c1-17(2,3)26-16(20)18-4-6-21-8-10-23-12-14-25-15-13-24-11-9-22-7-5-19/h19H,4-15H2,1-3H3,(H,18,20) |
InChI Key: | JJZYGSPDXUBTNO-UHFFFAOYSA-N |
Boiling Point: | 487.1±0.0 °C at 760 mmHg |
Purity: | ≥95% |
Density: | 1.087±0.06 g/cm3 (Predicted) |
Solubility: | Soluble in DCM, DMF, DMSO |
Appearance: | Pale Yellow or Colorless Oily Matter |
Storage: | Store at 2-8°C |
LogP: | 0.97730 |
Publication Number | Title | Priority Date |
WO-2020152067-A1 | Heterocyclic derivatives | 20190122 |
US-2019192668-A1 | Irak degraders and uses thereof | 20171226 |
US-10874743-B2 | IRAK degraders and uses thereof | 20171226 |
EP-2838534-A2 | Substituted benzamides and their uses | 20120412 |
US-2015072976-A1 | Substituted benzamides and their uses | 20120412 |
Complexity: | 322 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 381.23626707 |
Formal Charge: | 0 |
Heavy Atom Count: | 26 |
Hydrogen Bond Acceptor Count: | 8 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 381.23626707 |
Rotatable Bond Count: | 19 |
Topological Polar Surface Area: | 105 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.5 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Alcohols and Derivatives
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS