Salicylic acid - CAS 69-72-7
Catalog: |
BB033946 |
Product Name: |
Salicylic acid |
CAS: |
69-72-7 |
Synonyms: |
2-Carboxyphenol; 2-Hydroxybenzenecarboxylic acid; Advanced Pain Relief Callus Removers; Advanced Pain Relief Corn Removers; Clear away Wart Remover; Compound W; Dr.Scholl's Callus Removers; Dr. Scholl's Corn Removers; Dr. Scholl's Wart Remover Kit; Duofil Wart Remover; Duoplant; FM 110602; Freezone; Ionil; Ionil Plus; K 537; K 557; NSC 180; o-Carboxyphenol; o-Hydroxybenzoic acid; Phenol-2-carboxylic acid; Psoriacid-S-Stift; Retarder W; Rutranex; salicylic acid; Salicylic acid collodion; Salicylic Acid Soap; Saligel; Salonil; Salvona Nanosal; Stri-Dex; Trans-Ver-Sal; Verrugon |
Application: |
Anti-infective agents; antifungal agents; keratolytic agents |
IUPAC Name: | 2-hydroxybenzoic acid |
Description: | Salicylic acid is a natural product extract from Willow bark, well known as an antiinflammatory inhibitor of cyclooxygenase activity. It is widely used in organic synthesis and functions as a plant hormone and is known for its ability to ease aches and pains and reduce fevers. It is derived from the metabolism of salicin. It and its derivatives are used as constituents of some rubefacient products. In cosmetics, it has the effect of oil control, exfoliation, removing pimples, narrowing pores, and lightening marks. |
Molecular Weight: | 138.12 |
Molecular Formula: | C7H6O3 |
Canonical SMILES: | C1=CC=C(C(=C1)C(=O)O)O |
InChI: | InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10) |
InChI Key: | YGSDEFSMJLZEOE-UHFFFAOYSA-N |
Boiling Point: | ~211°C (approx) at 20 Torr |
Melting Point: | 157-159°C |
Flash Point: | 315 °F (157 °C) (closed cup) |
Purity: | >95% |
Density: | 1.443 g/cm3 |
Solubility: | Soluble in Ethanol |
Appearance: | White to off-white solid |
Storage: | Store at 2-8°C |
Decomposition: | When heated to decomp it emits acrid smoke and irritating fumes |
MDL: | MFCD00002439 |
LogP: | 1.09040 |
Quality Standard: | Enterprise Standard |
pH: | pH of saturated solution: 2.4 |
Refractive Index: | 1.565 |
Stability: | Stable. Substances to be avoided include oxidizing agents, strong bases, iodine, fluorine. Combustible. Sensitive to light. |
Vapor Pressure: | 1 mm Hg ( 114 °C) |
GHS Hazard Statement: | H302: Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P201, P202, P264, P270, P280, P281, P301+P312, P305+P351+P338, P308+P313, P310, P330, P405, and P501 |
Signal Word: | Danger |
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PMID | Publication Date | Title | Journal |
32227557 | 20200817 | The Selectivity of Fosfosal for STAT5b over STAT5a is Mediated by Arg566 in the Linker Domain | Chembiochem : a European journal of chemical biology |
32020584 | 20200501 | The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology | Immunology |
31734321 | 20200101 | CXCL14 downregulation in human keratinocytes is a potential biomarker for a novel in vitro skin sensitization test | Toxicology and applied pharmacology |
31334637 | 20190819 | Protective Role of Syzygium Cymosum Leaf Extract Against Carbofuran-Induced Hematological and Hepatic Toxicities | Chemical research in toxicology |
30842373 | 20190101 | Some non-sensitizers upregulate CD54 expression by activation of the NLRP3 inflammasome in THP-1 cells | The Journal of toxicological sciences |
Complexity: | 133 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 138.031694049 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 138.031694049 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 57.5 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.3 |
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