Salicylanilide - CAS 87-17-2
Catalog: |
BB038310 |
Product Name: |
Salicylanilide |
CAS: |
87-17-2 |
Synonyms: |
2-Hydroxybenzanilide; 2-(N-Phenylcarboxamido)phenol; 2-(Phenylaminocarbonyl)phenol; Ansadol; Aseptolan; Hyanilid; N-Phenyl-2-hydroxybenzamide; N-Phenylsalicylamide; NSC 14881; Salicylanilid; Salicylic acid anilide; Salifebrin; Salinide; Salinidol; Salnide; Shirlan; o-Hydroxybenzanilide |
Related CAS: | 2593-10-4 (sodium salt)
|
IUPAC Name: | 2-hydroxy-N-phenylbenzamide |
Description: | Salicylanilide has a wide range of biological activities, including antiviral, anti-inflammatory, antibacterial and so on. It inhibits HIV virus by targeting HIV-1 integrase or reverse transcriptase. It inhibits mycobacterial isocitrate lyase (ICL) and has a significant antimycobacterial effect. It can be used as an antiseptic. |
Molecular Weight: | 213.23 |
Molecular Formula: | C13H11NO2 |
Canonical SMILES: | C1=CC=C(C=C1)NC(=O)C2=CC=CC=C2O |
InChI: | InChI=1S/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16) |
InChI Key: | WKEDVNSFRWHDNR-UHFFFAOYSA-N |
Boiling Point: | 294.3±23.0°C at 760 mmHg |
Melting Point: | 136-138°C |
Flash Point: | 131.8±22.6 °C |
Purity: | ≥95% |
Density: | 1.278 g/cm3 |
Solubility: | Soluble in Chloroform (Slightly), Methanol (Slightly) |
Appearance: | White to Off-white Crystalline Solid |
Storage: | Store at -20°C under inert atmosphere |
MDL: | MFCD00002212 |
LogP: | 2.71750 |
Vapor Pressure: | 0.0±0.6 mmHg at 25°C |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P391, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-113332302-A | Veterinary insect repellent injection containing closantel sodium and ivermectin | 20210630 |
CN-113480882-A | Pure-color-imitated wall cloth art coating and manufacturing method thereof | 20210603 |
CN-113289020-A | Protein disulfide isomerase small-molecule inhibitor and application thereof | 20210517 |
CN-113183275-A | High-density fiberboard with antibacterial function and manufacturing process thereof | 20210511 |
CN-113004733-A | Antibacterial, mildewproof and flame-retardant silicate interior wall coating and preparation method thereof | 20210304 |
PMID | Publication Date | Title | Journal |
32533936 | 20201001 | Metabolic profiles of Oncomelania hupensis after molluscicidal treatment: Carbohydrate metabolism targeted and energy deficiency | Acta tropica |
30626902 | 20190109 | Repositioning salicylanilide anthelmintic drugs to treat adenovirus infections | Scientific reports |
28126437 | 20170215 | Novel salicylanilides from 4,5-dihalogenated salicylic acids: Synthesis, antimicrobial activity and cytotoxicity | Bioorganic & medicinal chemistry |
24333643 | 20140312 | Salicylanilide pyrazinoates inhibit in vitro multidrug-resistant Mycobacterium tuberculosis strains, atypical mycobacteria and isocitrate lyase | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences |
22970937 | 20121011 | Salicylanilide inhibitors of Toxoplasma gondii | Journal of medicinal chemistry |
Complexity: | 236 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 213.078978594 |
Formal Charge: | 0 |
Heavy Atom Count: | 16 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 213.078978594 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 49.3 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.3 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Carbonyl Compounds
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS