Salicylamide - CAS 65-45-2
Catalog: |
BB032734 |
Product Name: |
Salicylamide |
CAS: |
65-45-2 |
Synonyms: |
2-hydroxybenzamide |
IUPAC Name: | 2-hydroxybenzamide |
Description: | Hydrochlorothiazide Related Compound is a non-prescription drug with analgesic and antipyretic properties. It is used in combination with both aspirin and caffeine in the over-the-counter pain remedy "PainAid". |
Molecular Weight: | 137.14 |
Molecular Formula: | C7H7NO2 |
Canonical SMILES: | C1=CC=C(C(=C1)C(=O)N)O |
InChI: | InChI=1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10) |
InChI Key: | SKZKKFZAGNVIMN-UHFFFAOYSA-N |
Boiling Point: | 270 °C |
Melting Point: | 137-139 °C |
Purity: | > 95 % |
Density: | 1.175 g/cm3 |
Solubility: | less than 1 mg/mL at 68 °F |
Appearance: | Off-white solid |
Decomposition: | Dangerous; when heated to decomposition, It emits highly toxic fumes of /nitrogen oxides |
MDL: | MFCD00007978 |
LogP: | 1.19140 |
pH: | About 5 at 28 °c (aq soln) |
Stability: | Develops slight pink color on exposure to light, Therefore store in light resistant containers |
GHS Hazard Statement: | H302 (99.27%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501 |
Signal Word: | Warning |
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PMID | Publication Date | Title | Journal |
33374717 | 20201223 | Drug Repurposing Approach against Novel Coronavirus Disease (COVID-19) through Virtual Screening Targeting SARS-CoV-2 Main Protease | Biology |
27286660 | 20160901 | Activation of aryl hydrocarbon receptor reduces carbendazim-induced cell death | Toxicology and applied pharmacology |
27338550 | 20160601 | The anthelmintic niclosamide inhibits colorectal cancer cell lines via modulation of the canonical and noncanonical Wnt signaling pathway | The Journal of surgical research |
24389113 | 20140401 | A novel MDCKII in vitro model for assessing ABCG2-drug interactions and regulation of ABCG2 transport activity in the caprine mammary gland by environmental pollutants and pesticides | Toxicology in vitro : an international journal published in association with BIBRA |
23571415 | 20130601 | Structure-based identification of OATP1B1/3 inhibitors | Molecular pharmacology |
Complexity: | 136 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 137.047678466 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 137.047678466 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 63.3 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.3 |
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