CAS 1184173-73-6 (S)-N-[3-(6-Isopropoxy-3-pyridyl)-5-indazolyl]-1-[2-[4-[4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]-5,6-dihydropyridin-1(2H)-yl]-2-oxoethyl]-3-(methylthio)pyrrolidine-3-carboxamide

Catalog: BB004098
Product Name: (S)-N-[3-(6-Isopropoxy-3-pyridyl)-5-indazolyl]-1-[2-[4-[4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]-5,6-dihydropyridin-1(2H)-yl]-2-oxoethyl]-3-(methylthio)pyrrolidine-3-carboxamide
CAS: 1184173-73-6
Synonyms: (3S)-3-(methylthio)-1-[2-[4-[4-(1-methyl-1,2,4-triazol-3-yl)phenyl]-3,6-dihydro-2H-pyridin-1-yl]-2-oxoethyl]-N-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide; (3S)-3-methylsulfanyl-1-[2-[4-[4-(1-methyl-1,2,4-triazol-3-yl)phenyl]-3,6-dihydro-2H-pyridin-1-yl]-2-oxoethyl]-N-[3-(6-propan-2-yloxypyridin-3-yl)-1H-indazol-5-yl]pyrrolidine-3-carboxamide
Molecular Weight: 691.84
Molecular Formula: C37H41N9O3S
Canonical SMILES: CC(C)OC1=NC=C(C=C1)C2=NNC3=C2C=C(C=C3)NC(=O)C4(CCN(C4)CC(=O)N5CCC(=CC5)C6=CC=C(C=C6)C7=NN(C=N7)C)SC
InChI: InChI=1S/C37H41N9O3S/c1-24(2)49-32-12-9-28(20-38-32)34-30-19-29(10-11-31(30)41-42-34)40-36(48)37(50-4)15-18-45(22-37)21-33(47)46-16-13-26(14-17-46)25-5-7-27(8-6-25)35-39-23-44(3)43-35/h5-13,19-20,23-24H,14-18,21-22H2,1-4H3,(H,40,48)(H,41,42)/t37-/m0/s1
InChI Key: KPQQGHGDBBJGFA-QNGWXLTQSA-N
Description: MK-8353 is an orally available ERK1/2 inhibitor. It exhibited antitumor activity in patients with BRAFV600-mutant melanoma.

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(S)-N-[3-(6-Isopropoxy-3-pyridyl)-5-indazolyl]-1-[2-[4-[4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]-5,6-dihydropyridin-1(2H)-yl]-2-oxoethyl]-3-(methylthio)pyrrolidine-3-carboxamide - CAS 1184173-73-6