(S)-Ethyl 2-(((S)-1-(Benzyloxy)-1-oxopropan-2-yl-d3)amino)-4-oxo-4-phenylbutanoate
Catalog: |
BB065856 |
Product Name: |
(S)-Ethyl 2-(((S)-1-(Benzyloxy)-1-oxopropan-2-yl-d3)amino)-4-oxo-4-phenylbutanoate |
Synonyms: |
[S-(R*,R*)]-α-[[1-Methyl-2-oxo-2-(phenylmethoxy)ethyl]amino]-γ-oxo-benzenebutanoic Acid Ethyl Ester; (αS)-α-[[(1S)-1-Methyl-2-oxo-2-(phenylmethoxy)ethyl]amino]-γ-oxo-benzenebutanoic Acid Ethyl Ester |
Description: | (S)-Ethyl 2-(((S)-1-(Benzyloxy)-1-oxopropan-2-yl-d3)amino)-4-oxo-4-phenylbutanoate is an intermediate in the synthesis of Ramipril (R111000), an angiotensin converting enzyme (ACE) inhibitor, converted to active, diacid metabolite and an antihypertensive. |
Molecular Weight: | 386.46 |
Molecular Formula: | C22H22D3NO5 |
References: | Teetz, V., et al. Arzneim.-Forsch., 34, 1399 (1984); Ruggenenti, P., et al. Lancet, 352, (1998); Bosch, J., et al. Br. Med. J., 324, 1 (2002). |
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