(αS)-2-Chloro-α-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-4-nitro-1H-imidazole-1-ethanol - CAS 943610-37-5
Catalog: |
BB069995 |
Product Name: |
(αS)-2-Chloro-α-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-4-nitro-1H-imidazole-1-ethanol |
CAS: |
943610-37-5 |
Synonyms: |
(S)-(-)-1-(tert-Butyldimethylsilanyloxy)-3-(2-chloro-4-nitroimidazol-1-yl)propan-2-ol |
Description: | (αS)-2-Chloro-α-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-4-nitro-1H-imidazole-1-ethanol is an intermediate in the synthesis of (S)-PA 824 (P122500), a novel anti-tuberculosis drug. |
Molecular Weight: | 335.86 |
Molecular Formula: | C12H22ClN3O4Si |
Solubility: | DCM, Ethyl Acetate |
Appearance: | White Solid |
References: | Thompson, A. W., et al. Biorg. Med. Chem. Lett., 25, 3804 (2015). |
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