(R)-N-[2-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)phenyl]formamide - CAS 201677-59-0
Catalog: |
BB015683 |
Product Name: |
(R)-N-[2-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)phenyl]formamide |
CAS: |
201677-59-0 |
Synonyms: |
N-[5-[(1R)-2-bromo-1-hydroxyethyl]-2-phenylmethoxyphenyl]formamide; N-[5-[(1R)-2-bromo-1-hydroxyethyl]-2-phenylmethoxyphenyl]formamide |
IUPAC Name: | N-[5-[(1R)-2-bromo-1-hydroxyethyl]-2-phenylmethoxyphenyl]formamide |
Description: | (R)-N-[2-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)phenyl]formamide (CAS# 201677-59-0) is a key intermediate of (R,R)-Formoterol (rac: F693395). |
Molecular Weight: | 350.21 |
Molecular Formula: | C16H16BrNO3 |
Canonical SMILES: | C1=CC=C(C=C1)COC2=C(C=C(C=C2)C(CBr)O)NC=O |
InChI: | InChI=1S/C16H16BrNO3/c17-9-15(20)13-6-7-16(14(8-13)18-11-19)21-10-12-4-2-1-3-5-12/h1-8,11,15,20H,9-10H2,(H,18,19)/t15-/m0/s1 |
InChI Key: | HKSUZIIGCSOMPX-HNNXBMFYSA-N |
Boiling Point: | 559.644 °C at 760 mmHg |
Density: | 1.489 g/cm3 |
LogP: | 3.97110 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P264, P270, P301+P312, P330, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-110627673-A | Preparation method of formoterol key intermediate | 20180622 |
EP-3375781-A1 | Benzo ring derivative with b2 receptor agonist and m3 receptor antagonist activities and use thereof in medicine | 20150721 |
TW-201708211-A | Benzocyclo derivative having β 2 receptor agonism and M3 receptor antagonistic activity and its use in medicine | 20150721 |
US-2019185461-A1 | Benzocyclic derivative having b2-receptor agonist activity and m3-receptor antagonist activity and medical use thereof | 20150721 |
WO-2017012489-A1 | Benzo ring derivative with β2 receptor agonist and m3 receptor antagonist activities and use thereof in medicine | 20150721 |
Complexity: | 310 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 1 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 349.03136 |
Formal Charge: | 0 |
Heavy Atom Count: | 21 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 349.03136 |
Rotatable Bond Count: | 6 |
Topological Polar Surface Area: | 58.6 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.5 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Carbonyl Compounds
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS