(R)-3-Methylmorpholine Hydrochloride - CAS 953780-78-4
Catalog: |
BB041698 |
Product Name: |
(R)-3-Methylmorpholine Hydrochloride |
CAS: |
953780-78-4 |
Synonyms: |
(3R)-3-methylmorpholine;hydrochloride; (3R)-3-methylmorpholine;hydrochloride |
IUPAC Name: | (3R)-3-methylmorpholine;hydrochloride |
Description: | (R)-3-Methylmorpholine Hydrochloride (CAS# 953780-78-4) is used in the discovery studies of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally active GSK-3β inhibitors for Alzheimer's disease. |
Molecular Weight: | 137.61 |
Molecular Formula: | C5H12ClNO |
Canonical SMILES: | CC1COCCN1.Cl |
InChI: | InChI=1S/C5H11NO.ClH/c1-5-4-7-3-2-6-5;/h5-6H,2-4H2,1H3;1H/t5-;/m1./s1 |
InChI Key: | MSOCQCWIEBVSLF-NUBCRITNSA-N |
LogP: | 1.12550 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2020244539-A1 | Pyridone derivative, preparation method therefor, and pharmaceutical application thereof | 20190604 |
CN-113195728-A | Pharmaceutical process and intermediates | 20181218 |
KR-20210106461-A | Pharmaceutical processes and intermediates | 20181218 |
CN-113164476-A | Small molecule inhibitor of DYRK1/CLK and application thereof | 20180928 |
US-2020039989-A1 | Small molecule inhibitors of dyrk/clk and uses thereof | 20180301 |
Complexity: | 56 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 2 |
Defined Atom Stereocenter Count: | 1 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 137.0607417 |
Formal Charge: | 0 |
Heavy Atom Count: | 8 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 137.0607417 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 21.3 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
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Morpholines/Thiomorpholines
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