(R)-3-(Hydroxymethyl)pyrrolidine - CAS 110013-18-8
Catalog: |
BB002579 |
Product Name: |
(R)-3-(Hydroxymethyl)pyrrolidine |
CAS: |
110013-18-8 |
Synonyms: |
[(3R)-3-pyrrolidinyl]methanol; [(3R)-pyrrolidin-3-yl]methanol |
IUPAC Name: | [(3R)-pyrrolidin-3-yl]methanol |
Description: | (R)-3-(Hydroxymethyl)pyrrolidine (CAS# 110013-18-8) is a reagent used in the preparation of BET bromodomain inhibitors as well as highly potent α,α-disubstituted amino acid-based arginase inhibitors. |
Molecular Weight: | 101.15 |
Molecular Formula: | C5H11NO |
Canonical SMILES: | C1CNCC1CO |
InChI: | InChI=1S/C5H11NO/c7-4-5-1-2-6-3-5/h5-7H,1-4H2/t5-/m1/s1 |
InChI Key: | QOTUIIJRVXKSJU-RXMQYKEDSA-N |
Boiling Point: | 176 °C |
Density: | 0.978 g/cm3 |
Solubility: | Slightly soluble in water. |
Appearance: | White to yellow solid |
Storage: | Keep in dark place, Inert atmosphere, 2-8 °C |
MDL: | MFCD09607969 |
LogP: | -0.08300 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-111808007-A | Preparation method of chiral 3-substituted pyrrolidine derivative | 20200623 |
WO-2021115444-A1 | MONOCYCLIC β-LACTAM COMPOUND AND USE THEREOF | 20191213 |
WO-2021116446-A1 | Functionalized heterocyclic compounds as modulators of stimulator of interferon genes (sting) | 20191211 |
WO-2021098817-A1 | Dioxopiperazine derivative, preparation method therefore and pharmaceutical use thereof | 20191121 |
WO-2020123395-A1 | 2-oxoquinazoline derivatives as methionine adenosyltransferase 2a inhibitors | 20181210 |
Complexity: | 56 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 1 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 101.084063974 |
Formal Charge: | 0 |
Heavy Atom Count: | 7 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 101.084063974 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 32.3 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.5 |
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