(R)-(+)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde - CAS 95715-87-0

Name: (R)-(+)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB041825
Product Name:	(R)-(+)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde
CAS:	95715-87-0
Synonyms:	tert-butyl (4R)-4-formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

Technical Data

IUPAC Name:	tert-butyl (4R)-4-formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
Description:	Intermediate in the preparation of various enzymatic inhibitors.
Molecular Weight:	229.27
Molecular Formula:	C11H19NO4
Canonical SMILES:	CC1(N(C(CO1)C=O)C(=O)OC(C)(C)C)C
InChI:	InChI=1S/C11H19NO4/c1-10(2,3)16-9(14)12-8(6-13)7-15-11(12,4)5/h6,8H,7H2,1-5H3/t8-/m0/s1
InChI Key:	PNJXYVJNOCLJLJ-QMMMGPOBSA-N
Boiling Point:	302.7 °C at 760 mmHg
Flash Point:	102 °C(215.6 °F)
Purity:	95 %
Density:	1.06 g/cm³
Appearance:	Colourless oil
Storage:	Inert atmosphere. Keep cold.
MDL:	MFCD00674064
LogP:	1.49520
Refractive Index:	1.445

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
WO-2021113492-A1	Cyclic compounds and methods of using same	20191206
WO-2021014380-A1	Arginase inhibitors and methods of use thereof	20190723
WO-2020167984-A1	Bicyclic sulfonamides	20190214
WO-2019082209-A1	STABLE N- ((1R, 2R) -1- (2,3-DIHYDROBENZO [B] [1,4] DIOXIN-6-YL) N-(2R, 3R) -2,3-DIHYDROXYSUCCINATE PREMIXE - 1-HYDROXY-3- (PYRROLIDIN-1-YL) PROPAN-2-YL) AND PROCESS FOR PREPARING THE SAME	20171027
US-2020306225-A1	Stable n-((1r,2r)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl) octanamide (2r,3r)-2,3-dihydroxysuccinate premix and process for preparation thereof	20171027

PMID	Publication Date	Title	Journal
22954071	20120921	De novo synthesis of the bacterial 2-amino-2,6-dideoxy sugar building blocks D-fucosamine, D-bacillosamine, and D-xylo-6-deoxy-4-ketohexosamine	Organic letters
21404349	20110418	A synthetic route to highly substituted 1,2,3,4-tetrahydroisoquinolines via Yb(OTf)3 -catalyzed diastereoselective ring opening of bridged oxazolidines: asymmetric synthesis of 2-azapodophyllotoxin	Chemistry (Weinheim an der Bergstrasse, Germany)
17411060	20070426	Synthesis and absolute structure of manzacidin B	Organic letters
17249735	20070302	Synthesis of borondipyrromethene (BODIPY)-labeled sphingosine derivatives by cross-metathesis reaction	The Journal of organic chemistry
16836391	20060720	An efficient high-yield synthesis of D-ribo-phytosphingosine	Organic letters

Complexity:	293
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	1
Defined Bond Stereocenter Count:	0
Exact Mass:	229.13140809
Formal Charge:	0
Heavy Atom Count:	16
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	0
Isotope Atom Count:	0
Monoisotopic Mass:	229.13140809
Rotatable Bond Count:	3
Topological Polar Surface Area:	55.8 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1