(R)-3-(3-Fluorophenyl)-5-(hydroxymethyl)-2-oxazolidinone - CAS 149524-42-5
Catalog: |
BB010420 |
Product Name: |
(R)-3-(3-Fluorophenyl)-5-(hydroxymethyl)-2-oxazolidinone |
CAS: |
149524-42-5 |
Synonyms: |
(5R)-3-(3-fluorophenyl)-5-(hydroxymethyl)-2-oxazolidinone; (5R)-3-(3-fluorophenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one |
IUPAC Name: | (5R)-3-(3-fluorophenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one |
Description: | One of the impurities of Tedizolid, which has been found to be an antibacterial agent and could be effective in the treatment of bacterial skin infections. |
Molecular Weight: | 211.19 |
Molecular Formula: | C10H10FNO3 |
Canonical SMILES: | C1C(OC(=O)N1C2=CC(=CC=C2)F)CO |
InChI: | InChI=1S/C10H10FNO3/c11-7-2-1-3-8(4-7)12-5-9(6-13)15-10(12)14/h1-4,9,13H,5-6H2/t9-/m1/s1 |
InChI Key: | XYUGDJIYKLSISX-SECBINFHSA-N |
Boiling Point: | 341.2 °C at 760 mmHg |
Purity: | 98 % |
Density: | 1.368 g/cm3 |
Appearance: | Solid |
MDL: | MFCD08234640 |
LogP: | 1.20820 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CA-3024531-A1 | Topical formulations of biaryl heterocyclic compounds and methods of use thereof | 20160517 |
TW-201806595-A | Partial formulation of biaryl heterocyclic compound and method of use thereof | 20160517 |
US-2017333400-A1 | Topical formulations of biaryl heterocyclic compounds and methods of use thereof | 20160517 |
US-2019358206-A1 | Topical formulations of biaryl heterocyclic compounds and methods of use thereof | 20160517 |
US-10385079-B2 | Preparation method for tedizolid, tedizolid intermediate, and preparation method therefor | 20151103 |
Complexity: | 249 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 1 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 211.06447134 |
Formal Charge: | 0 |
Heavy Atom Count: | 15 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 211.06447134 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 49.8 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.9 |
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