sn-Glycero-3-phosphocholine - CAS 28319-77-9

Name: sn-Glycero-3-phosphocholine
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB019813
Product Name:	sn-Glycero-3-phosphocholine
CAS:	28319-77-9
Synonyms:	Choline alfoscerate; (R)-2-[[(2,3-Dihydroxypropoxy)hydroxyphosphinyl]oxy]-N,N,N-trimethylethanaminium Inner Salt; 2-[[[(2R)-2,3-Dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethylethanaminium Inner Salt; Brezal; Cereton; Cholicerin; Cholitiline; Delecit; Glycerylphosphocholine; L-α-GPC; L-α-Glycerophosphocholine; L-α-Glycerylphosphorylcholine; O-(sn-glycero-3-Phosphoryl)choline; Sn-Glycerophosphocholine; sn-Glycero-3-phosphorylcholine; α-Glycerophosphorylcholine; α-Glycerylphosphorylcholine
Application:	Ingredient of health care products.

Technical Data

IUPAC Name:	[(2R)-2,3-dihydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
Description:	sn-Glycero-3-phosphocholine is a nootropic phospholipid and acts as a precursor to choline biosynthesis. sn-Glycero-3-phosphocholine is an intermediate in catabolic pathway of phosphatidylcholine. Nutritional supplement in health care products.
Molecular Weight:	257.22
Molecular Formula:	C8H20NO6P
Canonical SMILES:	C[N+](C)(C)CCOP(=O)([O-])OCC(CO)O
InChI:	InChI=1S/C8H20NO6P/c1-9(2,3)4-5-14-16(12,13)15-7-8(11)6-10/h8,10-11H,4-7H2,1-3H3/t8-/m1/s1
InChI Key:	SUHOQUVVVLNYQR-MRVPVSSYSA-N
Melting Point:	130-134°C (dec.)
Purity:	≥95%
Solubility:	Soluble in DMSO (Slightly, Heated, Sonicated), Methanol (Sparingly), Water (Sparingly)
Appearance:	White to Off-white Solid
Storage:	Store at -20°C
LogP:	-0.38240

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CN-113354678-A	Preparation method of glycerophosphorylcholine	20210413

PMID	Publication Date	Title	Journal
33617914	20210415	Decrease of an intracellular organic osmolyte contributes to the cytotoxicity of organophosphate in neuroblastoma cells in vitro	Toxicology
30639121	20190301	The effect of repeated isoflurane exposure on serine synthesis pathway during the developmental period in Caenorhabditis elegans	Neurotoxicology
25482527	20140101	EDI3 links choline metabolism to integrin expression, cell adhesion and spreading	Cell adhesion & migration
23528616	20130607	Dietary exposure to a low dose of pesticides alone or as a mixture: the biological metabolic fingerprint and impact on hematopoiesis	Toxicology
22549883	20121201	Blast-induced neurotrauma leads to neurochemical changes and neuronal degeneration in the rat hippocampus	NMR in biomedicine

Complexity:	233
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	1
Defined Bond Stereocenter Count:	0
Exact Mass:	257.10282436
Formal Charge:	0
Heavy Atom Count:	16
Hydrogen Bond Acceptor Count:	6
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	257.10282436
Rotatable Bond Count:	8
Topological Polar Surface Area:	99
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	-2.3