(R)-1-(Tetrahydro-2H-pyran-4-yl)ethanamine - CAS 1269755-01-2

Name: (R)-1-(Tetrahydro-2H-pyran-4-yl)ethanamine
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB056866
Product Name:	(R)-1-(Tetrahydro-2H-pyran-4-yl)ethanamine
CAS:	1269755-01-2
Synonyms:	(αR)-Tetrahydro-α-methyl-2H-pyran-4-methanamine

Technical Data

Safety and Hazards

Patents

Computed Properties

IUPAC Name:	(1R)-1-(oxan-4-yl)ethanamine
Description:	(R)-1-(Tetrahydro-2H-pyran-4-yl)ethanamine is used in the prepartion of novel 3-quinoline carboxamides as potent, selective and orally bioavailable inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase.
Molecular Weight:	129.2
Molecular Formula:	C7H15NO
Canonical SMILES:	CC(C1CCOCC1)N
InChI:	InChI=1S/C7H15NO/c1-6(8)7-2-4-9-5-3-7/h6-7H,2-5,8H2,1H3/t6-/m1/s1
InChI Key:	WMPAKQDIADKRAQ-ZCFIWIBFSA-N
References:	Degorce, Sebastien L., et al. J Med Chem., 59, 628 (2016).

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Other Building Blocks

[88563-82-0]C9H11Br
1- (1- Bromoethyl) - 3- methylbenzene
[128076-60-8]C8H8INO
1- (2- Aminophenyl) - 2- iodoethanone
[53157-48-5]C15H20N2O3
N-tert-Butoxycarbonyl Serotonin
[6332-13-4]C9H13NO
4-Aminophenyl Ethyl Carbinol
[86271-48-9]C9H19NO3
5-[Bis(2-hydroxyethyl)amino]-2-pentanone
[548777-18-0]C9H9NO2
1-(Pent-4-yn-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

GHS Hazard Statement:	H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
Precautionary Statement:	P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501
Signal Word:	Danger

Publication Number	Title	Priority Date
CA-3017035-A1	Cinnolin-4-amine compounds and their use in treating cancer	20160321
JP-2019512512-A	Cinnolin-4-amine compounds and their use in cancer treatment	20160321
KR-20180127419-A	Cinnolin-4-amine compounds and uses thereof for treating cancer	20160321
US-2019099421-A1	Cinnolin-4-amine compounds and their use in treating cancer	20160321
EP-3168219-A1	Pyridone derivative having tetrahydropyranyl methyl group	20140707
US-10442797-B2	Pyridone derivatives having tetrahydropyranylmethyl groups	20140707
US-2017183329-A1	Pyridone derivative having tetrahydropyranylmethyl group	20140707
US-2018148436-A2	Pyridone derivatives having tetrahydropyranylmethyl groups	20140707
US-2020010458-A1	Pyridone derivatives having tetrahydropyranylmethyl groups	20140707
EP-3168219-B1	Pyridone derivative having tetrahydropyranyl methyl group	20140707

Complexity:	79
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	1
Defined Bond Stereocenter Count:	0
Exact Mass:	129.115364102
Formal Charge:	0
Heavy Atom Count:	9
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	1
Isotope Atom Count:	0
Monoisotopic Mass:	129.115364102
Rotatable Bond Count:	1
Topological Polar Surface Area:	35.2Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	0.3