(R)-(-)-1,2-Propanediol - CAS 4254-14-2
Catalog: |
BB025159 |
Product Name: |
(R)-(-)-1,2-Propanediol |
CAS: |
4254-14-2 |
Synonyms: |
(-)-1,2-Propanediol; (-)-Propylene Glycol; (2R)-1,2-Propanediol; (R)-1,2-Propanediol; (R)-2-Hydroxy-1-propanol; (R)-Propylene Gycol; 1-Deoxy-sn-glycerol; D-(-)-Propanediol; NSC 90793 |
Related CAS: | 57-55-6 (rac-isomer)
|
IUPAC Name: | (2R)-propane-1,2-diol |
Description: | It has been widely used as a solvent, extractant and preservative in a variety of parenteral and nonparenteral pharmaceutical formulations. |
Molecular Weight: | 76.09 |
Molecular Formula: | C3H8O2 |
Canonical SMILES: | CC(CO)O |
InChI: | InChI=1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3/t3-/m1/s1 |
InChI Key: | DNIAPMSPPWPWGF-GSVOUGTGSA-N |
Boiling Point: | 187 °C |
Melting Point: | -60 °C |
Purity: | ≥95% |
Density: | 1.04 g/cm3 |
Solubility: | Miscible with Acetone, Chloroform, Ethanol (95%), Glycerin, Water |
Appearance: | Colorless liquid |
Storage: | Store at RT |
MDL: | MFCD00066248 |
LogP: | -0.64050 |
GHS Hazard Statement: | H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] |
Precautionary Statement: | P264+P265, P280, P305+P351+P338, and P337+P317 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
US-2016175284-A1 | Estrogen receptor modulators and uses thereof | 20141218 |
WO-2015173247-A1 | New microorganism and method for the production of 1.2-propanediol based on nadph dependent acetol reductase and improved nadph supply | 20140512 |
WO-2015175075-A1 | Reduced central corneal thickening by use of hydrophilic ester prodrugs of beta-chlorocyclopentanes | 20140220 |
US-2015111852-A1 | 1-Di(sec-butyl)-phosphinoyl-pentane (dapa-2-5) as a topical agent... | 20131022 |
US-2014275082-A1 | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 20130314 |
PMID | Publication Date | Title | Journal |
23107503 | 20121015 | Microbial ecology of sorghum sourdoughs: effect of substrate supply and phenolic compounds on composition of fermentation microbiota | International journal of food microbiology |
22398860 | 20120701 | L-pantoyl lactone dehydrogenase from Rhodococcus erythropolis: genetic analyses and application to the stereospecific oxidation of L-pantoyl lactone | Applied microbiology and biotechnology |
22757713 | 20120701 | Influence of sodium chloride, pH, and lactic acid bacteria on anaerobic lactic acid utilization during fermented cucumber spoilage | Journal of food science |
22410135 | 20120601 | Varying amounts of different aldehydes present in the cryoprotectants dimethyl sulphoxide and 1,2-propanediol | Cryobiology |
22366381 | 20120510 | Characterization and evaluation of self-microemulsifying sustained-release pellet formulation of puerarin for oral delivery | International journal of pharmaceutics |
Complexity: | 20.9 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 1 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 76.052429494 |
Formal Charge: | 0 |
Heavy Atom Count: | 5 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 76.052429494 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 40.5 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.9 |
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