Oxolane-3-sulfonamide - CAS 1311316-50-3

Name: Oxolane-3-sulfonamide
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB058432
Product Name:	Oxolane-3-sulfonamide
CAS:	1311316-50-3
Synonyms:	Tetrahydro-3-furansulfonamide

Technical Data

IUPAC Name:	oxolane-3-sulfonamide
Description:	Oxolane-3-sulfonamide is used in preparation of Azabicycloheptanyloxymethyl Pyrazoles, Triazoles and related compounds; which are used as hormone receptor modulators treatment and prevention of FXR-mediated diseases. Also, used in preparation of N-Sulfonylated pyrazolo[3,4-b]pyridine-6-carboxamides as CFTR modulators.
Molecular Weight:	151.18
Molecular Formula:	C4H9NO3S
Canonical SMILES:	C1COCC1S(=O)(=O)N
InChI:	InChI=1S/C4H9NO3S/c5-9(6,7)4-1-2-8-3-4/h4H,1-3H2,(H2,5,6,7)
InChI Key:	GMAXVRALICXRLK-UHFFFAOYSA-N
References:	Chao, J., et al. PCT Int. Appl., (2019); Akkari, R., et al. PCT Int. Appl., (2017).

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
WO-2019084300-A1	TREATMENT OF GLIOBLASTOMA WITH FASN INHIBITORS	20171025
US-2021380585-A1	Hormone receptor modulators for treating metabolic mutagenic and fibrotic conditions and disorders	20170914
US-2019233420-A1	Hormone receptor modulators for treating metabolic conditions and disorders	20160823
US-10793568-B2	Hormone receptor modulators for treating metabolic conditions and disorders	20160823
US-2021017177-A1	Hormone receptor modulators for treating metabolic conditions and disorders	20160823
AU-2016333856-A1	N-sulfonylated pyrazolo[3,4-b]pyridin-6-carboxamides and method of use	20151009
US-10259810-B2	N-sulfonylated pyrazolo[3,4-b]pyridin-6-carboxamides and method of use	20151009
US-10647717-B2	N-sulfonylated-pyrazolo[3,4-b]pyridin-6-carboxamides and method of use	20151009
US-2017101405-A1	N-SULFONYLATED PYRAZOLO[3,4-b]PYRIDIN-6-CARBOXAMIDES AND METHOD OF USE	20151009
US-2018105522-A1	N-SULFONYLATED PYRAZOLO[3,4-b]PYRIDIN-6-CARBOXAMIDES AND METHOD OF USE	20151009

Complexity:	181
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	151.03031432
Formal Charge:	0
Heavy Atom Count:	9
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	1
Isotope Atom Count:	0
Monoisotopic Mass:	151.03031432
Rotatable Bond Count:	1
Topological Polar Surface Area:	77.8Å²
Undefined Atom Stereocenter Count:	1
Undefined Bond Stereocenter Count:	0
XLogP3:	-1