O-Trimethyl GFT-505 - CAS 923978-25-0

Catalog: BB057144
Product Name: O-Trimethyl GFT-505
CAS: 923978-25-0
Synonyms: 2-[2,6-Dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl-propanoic Acid 1,1-Dimethylethyl Ester; (E)-t-Butyl 2-(2,6-Dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxoprop-1-en-1-yl)phenoxy)-2-methylpropanoate
Description:O-Trimethyl GFT-505 is an intermediate in synthesizing GFT-505 (G368870), which is a dual PPARα/δ agonist. Studies have shown that GFT-505 improves hepatic and peripheral insulin sensitivity in abdominally obese subjects. It may also be a potential new drug candidate for treating lipid and glucose disorders.
Molecular Weight:440.59
Molecular Formula:C26H32O4S
Solubility:DCM, Methanol
Appearance:Off-White Solid
References:Carious, B., et al.: Diabetes Care 36, 2923 (2013); Carious, B., et al.: Diabetes Care 34, 2008 (2011).

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