O-(Trifluoroacetyl)-N-hydroxysuccinimide - CAS 5672-89-9
Catalog: |
BB057268 |
Product Name: |
O-(Trifluoroacetyl)-N-hydroxysuccinimide |
CAS: |
5672-89-9 |
Synonyms: |
1-[(Trifluoroacetyl)oxy]-2,5-pyrrolidinedione; N-(Trifluoroacetoxy)-succinimide; N-(Trifluoroacetoxy)succinimide; N-(Trifluoroacetyloxy)succinimide; N-Hydroxysuccinimide Trifluoroacetate; Trifluoroacetic Acid Succinimidyl Ester |
IUPAC Name: | (2,5-dioxopyrrolidin-1-yl) 2,2,2-trifluoroacetate |
Description: | O-(Trifluoroacetyl)-N-hydroxysuccinimide is used to prepare fluorinated xanthene derivatives as fluorescent dyes with use in staining biological materials. |
Molecular Weight: | 211.1 |
Molecular Formula: | C6H4F3NO4 |
Canonical SMILES: | C1CC(=O)N(C1=O)OC(=O)C(F)(F)F |
InChI: | InChI=1S/C6H4F3NO4/c7-6(8,9)5(13)14-10-3(11)1-2-4(10)12/h1-2H2 |
InChI Key: | NIANZCQUVKPGSF-UHFFFAOYSA-N |
References: | Gee, K., et al. PCT Int. Appl., WO 9739064 A1 19971023 (1997). |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 |
Signal Word: | Warning |
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PMID | Publication Date | Title | Journal |
21950593 | 20111104 | In situ formation of N-trifluoroacetoxy succinimide (TFA-NHS): one-pot formation of succinimidyl esters, N-trifluoroacetyl amino acid succinimidyl esters, and N-maleoyl amino acid succinimidyl esters | The Journal of organic chemistry |
Complexity: | 282 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 211.0092421 |
Formal Charge: | 0 |
Heavy Atom Count: | 14 |
Hydrogen Bond Acceptor Count: | 7 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 211.0092421 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 63.7Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.3 |
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