O-Isopropyl Chlorthalidone - CAS 2200280-98-2

Name: O-Isopropyl Chlorthalidone
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB060588
Product Name:	O-Isopropyl Chlorthalidone
CAS:	2200280-98-2
Synonyms:	Chlorthalidone Impurity H; 2-Chloro-5-[(1RS)-1-(1-mehtylethoxy)-3-oxo-2,3-dihydro-1H-isoindol-1-yl]benzenesulfonamide; 2-Chloro-5-(1-isopropoxy-3-oxoisoindolin-1-yl)benzenesulfonamide; 2-Chloro-5-[2,3-dihydro-1-(1-methylethoxy)-3-oxo-1H-isoindol-1-yl]benzenesulfonamide; Chlortalidone EP Impurity H

Technical Data

IUPAC Name:	2-chloro-5-(3-oxo-1-propan-2-yloxy-2H-isoindol-1-yl)benzenesulfonamide
Description:	An impurity of Chlorthalidone. Chlorthalidone is a long-acting thiazide-like diuretic used primarily for the treatment of hypertension and edema.
Molecular Weight:	380.85
Molecular Formula:	C17H17ClN2O4S
Canonical SMILES:	CC(C)OC1(C2=CC=CC=C2C(=O)N1)C3=CC(=C(C=C3)Cl)S(=O)(=O)N
InChI:	InChI=1S/C17H17ClN2O4S/c1-10(2)24-17(13-6-4-3-5-12(13)16(21)20-17)11-7-8-14(18)15(9-11)25(19,22)23/h3-10H,1-2H3,(H,20,21)(H2,19,22,23)
InChI Key:	QCLXXCMKIVGGRG-UHFFFAOYSA-N
Melting Point:	>216°C (dec.)
Purity:	≥95%
Density:	1.47±0.1 g/cm3
Solubility:	Soluble in DMSO (Slightly), Methanol (Slightly, Ultrasonic)
Appearance:	White to off-white solid
Storage:	Store at 2-8 °C
References:	Beisenherz, et al. Arch. Int. Pharmacodyn. Ther., 161, 76 (1966); Zsoter, et al. J. Pharmacol. Exp. Ther., 180, 723 (1972); Singer, J.M., et al. Anal. Profiles Drug Subs., 14, 1 (1985).