O'Ethly-N-boc-1-oxo-3-tertbutyldimethylsilyl-D-erythro-sphingosine

Catalog: BB056800
Product Name: O'Ethly-N-boc-1-oxo-3-tertbutyldimethylsilyl-D-erythro-sphingosine
Synonyms: (2R,3R,E)-Ethyl 2-((tert-Butoxycarbonyl)amino)-3-((tert-butyldimethylsilyl)oxy)octadec-4-enoate; D-erythro-Sphingosine-N-tert-butyloxycarbonyl-1-oxo-3-tert-butyldimethylsilyl Ethyl Ester
Description:D-erythro-Sphingosine-N-tert-butyloxycarbonyl-O-tert-butyldimethylsilyl Ethyl Ester is an intermediate formed in the synthesis of β-Galactosyl-C18-ceramide (G184960), which is a galactosylceramides that plays an important roles in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. They have shown to have significant immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma.
Molecular Weight:555.91
Molecular Formula:C31H61NO5Si
Solubility:DCM, Ethyl Acetate, Chloroform
Appearance:Colourless oil
Storage:-20°C Freezer
References:Morita, M., et al. J. Med. Chem., 38, 2176 (1995); Sakai, T., et al. J. Med. Chem., 42, 1836 (1999).

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