Nitroso-pyrazolone

Catalog:	BB058715
Product Name:	Nitroso-pyrazolone
Synonyms:	1-(3,4-Dimethylphenyl)-3-methyl-4-nitroso-1H-pyrazol-5-ol

Technical Data

Description:	1-(3,4-Dimethylphenyl)-3-methyl-4-nitroso-1H-pyrazol-5-ol is an intermediate used in the synthesis of N-Hydroxy Eltrombopag (H825795), which is a derivative compound of Eltrombopag (508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.
Molecular Weight:	231.25
Molecular Formula:	C12H13N3O2
Solubility:	Tetrahydrofuran; Chloroform
Appearance:	Orange Solid
Storage:	-20°C Freezer
References:	Bussel, J., et al. New Eng. J. Med., 357, 2237 (2007), Marsilje, T., et al. Bioorg. Med. Chem. Lett., 18, 5259 (2008), Alper, P., et al. Bioorg. Med. Chem. Lett., 18, 5255 (2008),.

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