Nipecotamide - CAS 4138-26-5

Catalog:	BB024871
Product Name:	Nipecotamide
CAS:	4138-26-5
Synonyms:	piperidine-3-carboxamide

Technical Data

Safety and Hazards

Patents

Literatures

Computed Properties

IUPAC Name:	piperidine-3-carboxamide
Description:	Nipecotamide (CAS# 4138-26-5) is a budiling blcok used in the sythnesis of various compounds, such as DPP-4 inhibitors, IKKβ inhibitors, piroimidazolidinone NPC1L1 inhibitors, and Anti-HIV agents.
Molecular Weight:	128.17
Molecular Formula:	C6H12N2O
Canonical SMILES:	C1CC(CNC1)C(=O)N
InChI:	InChI=1S/C6H12N2O/c7-6(9)5-2-1-3-8-4-5/h5,8H,1-4H2,(H2,7,9)
InChI Key:	BVOCPVIXARZNQN-UHFFFAOYSA-N
Boiling Point:	311.7 ℃ at 760 mmHg
Density:	1.06 g/cm³
MDL:	MFCD00005993
LogP:	0.50040

Publication Number	Title	Priority Date
CN-113185451-A	Memantine urea derivative and preparation method and application thereof	20210428
CN-111978242-A	Preparation method and application of (R) -3-aminopiperidine dihydrochloride	20200821
WO-2021191412-A1	Cathepsin substrates & cathepsin inhibitors and uses thereof	20200326
JP-2021150561-A	Abrasive and polishing method	20200323
CN-111763201-A	Benzothiazole compound and medical application thereof	20200303

PMID	Publication Date	Title	Journal
21459572	20110515	1,5-Substituted nipecotic amides: selective PDE8 inhibitors displaying diastereomer-dependent microsomal stability	Bioorganic & medicinal chemistry letters
15066183	20040401	A novel R-stereoselective amidase from Pseudomonas sp. MCI3434 acting on piperazine-2-tert-butylcarboxamide	European journal of biochemistry
11212124	20010212	Nipecotic and iso-nipecotic amides as potent and selective somatostatin subtype-2 receptor agonists	Bioorganic & medicinal chemistry letters

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Piperidines

[13617-02-2]
3-Bromo-1-methylpiperidine Hydrobromide
[313685-03-9]
Ethyl 1-[(4-chlorophenyl)sulfonyl]piperidine-4-carboxylate
[869951-27-9]
Ethyl 1-(ethylsulfonyl)piperidine-3-carboxylate
[832118-87-3]
Ethyl 1-(ethylsulfonyl)piperidine-4-carboxylate
[217487-18-8]
Ethyl 1-(methylsulfonyl)piperidine-4-carboxylate
[610259-52-4]
Ethyl 1-(thiophen-2-ylsulfonyl)piperidine-3-carboxylate

Customers Also Viewed

[30360-19-1]
N,N'-Diethyl-N''-isopropyl-1,3,5-triazine-2,4,6-triamine
[1263166-91-1]
endo-BCN-PNP-carbonate
[133407-82-6]
MG-132
[10128-55-9]
N-[2-(4-oxo-4H-3,1-benzoxazin-2-yl)phenyl]-2-naphthalenesulfonamide
[35153-16-3]
(Z)-10-Tetradecenyl Acetate
[16208-48-3]
Ethanesulfonic acid, 2,2'-trithiodi-, disodium salt

INDUSTRY LEADERS TRUST OUR PRODUCTS

Phone

US & Canada (Toll free):

UK:

International:

E-mail & Fax

E-mail:

Fax:

Address

USA:

UK:

Our Products

Inquiry Basket

Loading ......

Delete selected Go to checkout

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Complexity:	114
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	128.094963011
Formal Charge:	0
Heavy Atom Count:	9
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	128.094963011
Rotatable Bond Count:	1
Topological Polar Surface Area:	55.1 Å²
Undefined Atom Stereocenter Count:	1
Undefined Bond Stereocenter Count:	0
XLogP3:	-1.3