N2-[4-(Diethylamino)butyl]-6-(3,5-dimethoxyphenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine - CAS 862370-79-4
Catalog: |
BB067878 |
Product Name: |
N2-[4-(Diethylamino)butyl]-6-(3,5-dimethoxyphenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine |
CAS: |
862370-79-4 |
Synonyms: |
N2-[4-(Diethylamino)butyl]-6-(3,5-dimethoxyphenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine; 2-N-[4-(diethylamino)butyl]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidine-2,7-diamine |
IUPAC Name: | 2-N-[4-(diethylamino)butyl]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidine-2,7-diamine |
Description: | Used in the preparation of naphthyridinamines and related ureas as a selective FGFR1 and FGFR3 inhibitor. |
Molecular Weight: | 424.54 |
Molecular Formula: | C23H32N6O2 |
Canonical SMILES: | CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)N |
InChI: | InChI=1S/C23H32N6O2/c1-5-29(6-2)10-8-7-9-25-23-26-15-17-13-20(21(24)27-22(17)28-23)16-11-18(30-3)14-19(12-16)31-4/h11-15H,5-10H2,1-4H3,(H3,24,25,26,27,28) |
InChI Key: | NVRJYYIGIPJQMX-UHFFFAOYSA-N |
Melting Point: | 78-82°C |
Solubility: | Chloroform (Slightly), Methanol (Slightly) |
Appearance: | Yellow Solid |
Storage: | Refrigerator |
References: | Thompson, A. et al.; J. Med. Chem. 48, 4628 (2005). |
Complexity: | 497 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 424.25867428 |
Formal Charge: | 0 |
Heavy Atom Count: | 31 |
Hydrogen Bond Acceptor Count: | 8 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 424.25867428 |
Rotatable Bond Count: | 11 |
Topological Polar Surface Area: | 98.4Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.8 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Other Building Blocks
-
Maltotetraose Tridecaacetate
-
[1365727-07-6]
6-Methyldi(ondansetron-3-de(1,2-dimethyl-1H-imidazole))
-
[548777-18-0]
1-(Pent-4-yn-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
-
[1212679-29-2]
(3R,4R)-N-(3-Cyanophenyl)-3-[[4-[(4-fluorophenyl)methoxy]benzoyl]amino]hexahydro-4-hydroxy-1H-azepine-1-carboxamide
-
[1354469-76-3]
(3R,4R)-N,4-Dimethyl-piperidin-3-amine
-
[24177-07-9]
(2R,5S,10aS,10bS)-Octahydro-10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine-2-carboxylic Acid
Customers Also Viewed
-
[3886-90-6]
N,N-dimethyloctadecanamide
-
[883-44-3]
N-(3-Hydroxypropyl)phthalimide
-
[35045-02-4]
Metribuzin-desamino
-
[132182-92-4]
Pentane, 1,1,1,2,2,3,4,5,5,5-decafluoro-3-methoxy-4-(trifluoromethyl)-
-
[1427004-19-0]
DBCO-PEG4-NHS ester
-
[33229-34-4]
2,2'-[4-(2-Hydroxyethylamino)-3-nitrophenylimino]diethanol
INDUSTRY LEADERS TRUST OUR PRODUCTS