Description: | N-((R)-3-Methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)pyrazine-2-carboxamide is a useful synthetic intermediate in the synthesis of (R)-(3-Methyl-1-(pyrazine-2-carboxamido)butyl)boronic Acid (M327105); an impurity of Bortezomib (B675700) which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. |
Molecular Weight: | 371.28 |
Molecular Formula: | C20H30BN3O3 |
References: | Nawrocki, S.T., et al. Cancer Res., 65, 11510 (2005); Drahl, C. Chem. and Eng. News, 87, 41 (2009). |
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