IUPAC Name: | 1-(3,5-difluoropyridin-2-yl)-N-methylmethanamine |
Description: | N-Methyl-(3,5-difluoropyridin-2-yl)methaneamine is a synthetic block made from 3,5-Difluoropyridine-2-carbonitrile, which is used as a reactant in the preparation of pyrrolidones and indolinones via palladium-catalyzed intramolecular amination of unactivated C(sp3)-H and C(sp2)-H amide bonds. |
Molecular Weight: | 158.15 |
Molecular Formula: | C7H8F2N2 |
Canonical SMILES: | CNCC1=C(C=C(C=N1)F)F |
InChI: | InChI=1S/C7H8F2N2/c1-10-4-7-6(9)2-5(8)3-11-7/h2-3,10H,4H2,1H3 |
InChI Key: | QMEWZRYOPHAIRJ-UHFFFAOYSA-N |
References: | He, G., et al. Angew. Chem. Int. Ed., 52, 11124 (2013). |
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