N-Hydroxysulfosuccinimide sodium - CAS 106627-54-7
Catalog: |
BB001897 |
Product Name: |
N-Hydroxysulfosuccinimide sodium |
CAS: |
106627-54-7 |
Synonyms: |
Sulfo-NHS; Sodium 1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate |
Ordering Information
Catalog |
Size |
Price |
Stock |
BB001897 |
25 g |
$298 |
In stock |
Related CAS: | 82436-78-0 (free acid)
|
IUPAC Name: | sodium;1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate |
Description: | N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Molecular Weight: | 217.13 |
Molecular Formula: | C4H4NNaO6S |
Canonical SMILES: | C1C(C(=O)N(C1=O)O)S(=O)(=O)[O-].[Na+] |
InChI: | InChI=1S/C4H5NO6S.Na/c6-3-1-2(12(9,10)11)4(7)5(3)8;/h2,8H,1H2,(H,9,10,11);/q;+1/p-1 |
InChI Key: | RPENMORRBUTCPR-UHFFFAOYSA-M |
Melting Point: | 250 ℃ (dec.) |
Purity: | > 98.0 % |
Solubility: | 10 mm in DMSO |
Appearance: | Off-white to white powder |
Storage: | -20 ℃ |
MDL: | MFCD00043100 |
LogP: | -0.93300 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-113461813-A | Paired antibody for detecting new coronavirus and application thereof | 20210903 |
CN-113373025-A | Coating composition, device and method suitable for capturing rare cells | 20210811 |
CN-113499478-A | Method for processing biological tissue material | 20210707 |
CN-113466451-A | Kit for detecting anti-Prelamin A/C-IgG antibody | 20210701 |
CN-113376372-A | Immunofluorescence colloidal gold nano microsphere material | 20210616 |
PMID | Publication Date | Title | Journal |
22775561 | 20120904 | Nanoglue: an alternative way to display cell-internalizing peptide at the spikes of hepatitis B virus core nanoparticles for cell-targeting delivery | Molecular pharmaceutics |
22806464 | 20120701 | Studies on bioconjugation of quantum dots using capillary electrophoresis and fluorescence correlation spectroscopy | Electrophoresis |
22410116 | 20120530 | Bioactive hydrogels demonstrate mediated release of a chromophore by chymotrypsin | Journal of controlled release : official journal of the Controlled Release Society |
22541017 | 20120513 | Ultrasensitive detection of ovarian cancer marker using immunoliposomes and gold nanoelectrodes | Analytica chimica acta |
22081458 | 20120201 | Solution versus gas-phase modification of peptide cations with NHS-ester reagents | Journal of the American Society for Mass Spectrometry |
Complexity: | 331 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 2 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 216.96570230 |
Formal Charge: | 0 |
Heavy Atom Count: | 13 |
Hydrogen Bond Acceptor Count: | 6 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 216.96570230 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 123 Å2 |
Undefined Atom Stereocenter Count: | 1 |
Undefined Bond Stereocenter Count: | 0 |
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